{"id":54386,"date":"2023-07-18T09:10:29","date_gmt":"2023-07-18T16:10:29","guid":{"rendered":"https:\/\/www.chronobiology.com\/melatonin-och-kronobiologi\/melatonin-historia\/"},"modified":"2023-07-18T09:10:30","modified_gmt":"2023-07-18T16:10:30","slug":"melatonin-historia","status":"publish","type":"page","link":"https:\/\/dev.chronobiology.com\/sv\/melatonin-och-kronobiologi\/melatonin-historia\/","title":{"rendered":"Melatonin historia"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row full_width=&#8221;stretch_row&#8221; el_class=&#8221;banner-top&#8221; css=&#8221;.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}&#8221;][vc_column][vc_custom_heading source=&#8221;post_title&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row el_class=&#8221;melatoninfacts2&#8243;][vc_column][vc_column_text]<\/p>\n<h2 style=\"text-align: center;\">Historia<\/h2>\n<p>Melatonin produceras huvudsakligen av tallkottk\u00f6rteln (glandula pinealis). Detta organ omn\u00e4mns redan av Galen fr\u00e5n Pergamon och andra greker under andra \u00e5rhundradet. P\u00e5 1500-talet beskrev den franske filosofen och vetenskapsmannen Descartes tallkottk\u00f6rteln som sj\u00e4lens s\u00e4te.<\/p>\n<p>Melatonin i sig uppt\u00e4cktes f\u00f6rst 1958 av en hudl\u00e4kare vid namn Aaron Lerner och har sedan 1980-talet varit f\u00f6rem\u00e5l f\u00f6r omfattande forskning. Lerner lyckades isolera en f\u00f6rening i en bovin tallkottk\u00f6rtel som hade en starkt blekande effekt p\u00e5 amfibiehud, och han gav den namnet melatonin. Det var ocks\u00e5 Lerner som b\u00f6rjade studera hormonets effekt p\u00e5 s\u00f6mnen. Efter ett sj\u00e4lvf\u00f6rs\u00f6k med 100 mg melatonin rapporterade Lerner att han inte hade n\u00e5gra biverkningar f\u00f6rutom d\u00e5sighet. P\u00e5 1960-talet antog man fortfarande att ljus-m\u00f6rker-rytmen var viktig f\u00f6r d\u00e4ggdjur, men inte f\u00f6r m\u00e4nniskor. F\u00f6rst 1981 uppt\u00e4ckte Alfred Lewy att starkt ljus som applicerades p\u00e5 natten undertryckte endogent melatonin hos m\u00e4nniskor. Denna uppt\u00e4ckt var ett genombrott f\u00f6r kronobiologin och forskningen om melatonin. I b\u00f6rjan av 1990-talet fick hormonet allt st\u00f6rre uppm\u00e4rksamhet eftersom studier visade melatoninets effekter p\u00e5 olika kroppsliga processer, t.ex. immunmodulering, begr\u00e4nsning av tum\u00f6rtillv\u00e4xt, f\u00e5ngst av syreradikaler och p\u00e5verkan p\u00e5 kalciumberoende metaboliska processer. D\u00e4refter har ytterligare studier gjorts om melatonin och dess m\u00e5ngfacetterade inverkan p\u00e5 m\u00e4nniskors h\u00e4lsa.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row full_width=&#8221;stretch_row&#8221; el_class=&#8221;banner-top&#8221; css=&#8221;.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}&#8221;][vc_column][vc_custom_heading source=&#8221;post_title&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row el_class=&#8221;melatoninfacts2&#8243;][vc_column][vc_column_text] Historia Melatonin produceras huvudsakligen av tallkottk\u00f6rteln (glandula pinealis). Detta organ omn\u00e4mns redan av Galen fr\u00e5n Pergamon och andra greker under andra \u00e5rhundradet. P\u00e5 1500-talet beskrev den franske filosofen och vetenskapsmannen Descartes tallkottk\u00f6rteln som sj\u00e4lens s\u00e4te. Melatonin i sig uppt\u00e4cktes f\u00f6rst 1958 av en hudl\u00e4kare vid [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":48507,"parent":54326,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"full-width-content","footnotes":""},"categories":[326,324],"class_list":{"0":"post-54386","1":"page","2":"type-page","3":"status-publish","4":"has-post-thumbnail","6":"category-melatonin-sv","7":"category-somn","8":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.4 (Yoast SEO v23.4) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Melatonin historia &#8211; Chronobiology.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dev.chronobiology.com\/sv\/melatonin-och-kronobiologi\/melatonin-historia\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melatonin historia\" \/>\n<meta property=\"og:description\" content=\"[vc_row full_width=&#8221;stretch_row&#8221; el_class=&#8221;banner-top&#8221; css=&#8221;.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}&#8221;][vc_column][vc_custom_heading source=&#8221;post_title&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row el_class=&#8221;melatoninfacts2&#8243;][vc_column][vc_column_text] Historia Melatonin produceras huvudsakligen av tallkottk\u00f6rteln (glandula pinealis). Detta organ omn\u00e4mns redan av Galen fr\u00e5n Pergamon och andra greker under andra \u00e5rhundradet. P\u00e5 1500-talet beskrev den franske filosofen och vetenskapsmannen Descartes tallkottk\u00f6rteln som sj\u00e4lens s\u00e4te. 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Chronobiology.com","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/dev.chronobiology.com\/sv\/melatonin-och-kronobiologi\/melatonin-historia\/","og_locale":"sv_SE","og_type":"article","og_title":"Melatonin historia","og_description":"[vc_row full_width=&#8221;stretch_row&#8221; el_class=&#8221;banner-top&#8221; css=&#8221;.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}&#8221;][vc_column][vc_custom_heading source=&#8221;post_title&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row el_class=&#8221;melatoninfacts2&#8243;][vc_column][vc_column_text] Historia Melatonin produceras huvudsakligen av tallkottk\u00f6rteln (glandula pinealis). Detta organ omn\u00e4mns redan av Galen fr\u00e5n Pergamon och andra greker under andra \u00e5rhundradet. P\u00e5 1500-talet beskrev den franske filosofen och vetenskapsmannen Descartes tallkottk\u00f6rteln som sj\u00e4lens s\u00e4te. 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