{"id":58489,"date":"2017-01-27T10:14:53","date_gmt":"2017-01-27T18:14:53","guid":{"rendered":"https:\/\/www.chronobiology.com\/insecticide-exposure-creating-higher-risk-diabetes\/"},"modified":"2024-07-18T14:52:21","modified_gmt":"2024-07-18T21:52:21","slug":"exposition-aux-insecticides-un-risque-accru-de-diab-te","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/exposition-aux-insecticides-un-risque-accru-de-diab-te\/","title":{"rendered":"Exposition aux insecticides : Un risque accru de diab\u00e8te"},"content":{"rendered":"

Il existe de nombreuses raisons de limiter son exposition aux insecticides. Selon une nouvelle \u00e9tude, l’interf\u00e9rence avec les voies de la m\u00e9latonine et un risque plus \u00e9lev\u00e9 de diab\u00e8te pourraient en faire partie.<\/p>\n

Que savez-vous des ingr\u00e9dients contenus dans vos insecticides pr\u00e9f\u00e9r\u00e9s ? Le carbaryl et le carbofuran sont des ingr\u00e9dients communs \u00e0 de nombreux insecticides et ont fait l’objet d’une \u00e9tude r\u00e9cente. Ces insecticides sont tous deux chimiquement similaires \u00e0 la m\u00e9latonine, l’hormone qui r\u00e9gule le sommeil, le m\u00e9tabolisme et toute une s\u00e9rie d’autres processus biologiques importants. En fait, ils sont tous deux si semblables \u00e0 la m\u00e9latonine qu’ils peuvent se lier \u00e0 ses r\u00e9cepteurs<\/a> et provoquer certaines des m\u00eames r\u00e9actions. Cette activation des r\u00e9cepteurs de la m\u00e9latonine peut entra\u00eener une perturbation du rythme circadien et le syndrome m\u00e9tabolique, entre autres effets n\u00e9fastes.<\/p>\n

M\u00e9latonine et radicaux libres<\/h2>\n

La plupart des gens associent la m\u00e9latonine au sommeil. Si cette hormone joue un r\u00f4le tr\u00e8s important en pr\u00e9parant notre corps \u00e0 dormir la nuit<\/a> et en nous aidant \u00e0 prendre le repos dont nous avons besoin, elle joue \u00e9galement d’autres r\u00f4les dans la sant\u00e9 humaine. La m\u00e9latonine indique \u00e0 nos cellules qu’il est temps de r\u00e9parer l’ADN, de lib\u00e9rer les toxines accumul\u00e9es au cours de la journ\u00e9e et de r\u00e9cup\u00e9rer de mani\u00e8re \u00e0 ce que nous puissions nous r\u00e9veiller en pleine forme. La m\u00e9latonine joue \u00e9galement un r\u00f4le tr\u00e8s important dans la r\u00e9gulation de nos activit\u00e9s m\u00e9taboliques<\/a>. C’est la raison pour laquelle les personnes qui travaillent en \u00e9quipe<\/a> ou qui ne dorment pas suffisamment courent un risque plus \u00e9lev\u00e9 de d\u00e9velopper un diab\u00e8te et d’autres maladies m\u00e9taboliques.<\/p>\n

L’un des r\u00f4les les moins connus mais les plus importants de la m\u00e9latonine est celui de pi\u00e9geur de radicaux libres<\/a>, ou antioxydant. Nos cellules produisent des formes r\u00e9actives d’oxyg\u00e8ne au cours des r\u00e9actions m\u00e9taboliques quotidiennes. S’ils ne sont pas \u00e9limin\u00e9s, ces radicaux peuvent endommager les cellules de fa\u00e7on permanente. Pire encore, elles peuvent endommager l’ADN et conduire au cancer ainsi qu’\u00e0 d’autres maladies graves. La m\u00e9latonine nous prot\u00e8ge des toxines pr\u00e9sentes dans notre environnement et dans notre propre corps, tout en nous aidant \u00e0 nous reposer et \u00e0 nous r\u00e9g\u00e9n\u00e9rer. Cette hormone ayant de nombreux r\u00f4les \u00e0 jouer dans la sant\u00e9, l’exposition \u00e0 des produits chimiques qui d\u00e9clenchent les r\u00e9cepteurs de la m\u00e9latonine peut avoir des effets n\u00e9fastes sur la sant\u00e9.<\/p>\n

Comment les insecticides peuvent-ils augmenter le risque de diab\u00e8te ?<\/h2>\n

\"Insecticide<\/a>Si la m\u00e9latonine est bonne, comment les produits chimiques qui l’imitent peuvent-ils \u00eatre mauvais ? Comme dans de nombreux domaines, le choix du moment est primordial. Les quantit\u00e9s de m\u00e9latonine lib\u00e9r\u00e9es et les moments o\u00f9 elles le sont sont tous deux \u00e9troitement contr\u00f4l\u00e9s dans notre corps, car ils sont importants pour son fonctionnement. La m\u00e9latonine est lib\u00e9r\u00e9e en quantit\u00e9s tr\u00e8s pr\u00e9cises et \u00e0 des moments tr\u00e8s pr\u00e9cis, en r\u00e9ponse \u00e0 des signaux internes et \u00e0 des informations provenant de notre environnement. Lorsque ces insecticides se lient aux r\u00e9cepteurs de la m\u00e9latonine, ils induisent des activit\u00e9s au mauvais moment et dans les mauvaises quantit\u00e9s. En outre, les boucles de r\u00e9troaction n\u00e9gative qui r\u00e9gissent les niveaux de m\u00e9latonine peuvent \u00eatre affect\u00e9es, ce qui entra\u00eene une moindre lib\u00e9ration de m\u00e9latonine lorsqu’elle est r\u00e9ellement n\u00e9cessaire.<\/p>\n

Selon l’auteur principal de l’\u00e9tude, Margarita L. Dubocovitch, PhD,<\/p>\n

\n

\u00ab\u00a0En interagissant directement avec les r\u00e9cepteurs de la m\u00e9latonine dans le cerveau et les tissus p\u00e9riph\u00e9riques, les produits chimiques environnementaux, tels que le carbaryl, peuvent perturber des processus physiologiques cl\u00e9s, entra\u00eenant un d\u00e9salignement des rythmes circadiens, des sch\u00e9mas de sommeil et une alt\u00e9ration des fonctions m\u00e9taboliques, ce qui augmente le risque de maladies chroniques telles que le diab\u00e8te et les troubles m\u00e9taboliques.\u00a0\u00bb<\/p>\n<\/blockquote>\n

Un faible taux de m\u00e9latonine accro\u00eet le risque de diab\u00e8te<\/a> et la m\u00e9latonine lib\u00e9r\u00e9e au mauvais moment peut avoir un effet similaire.<\/p>\n

Ces insecticides sont-ils les seuls produits chimiques \u00e0 avoir cet effet ? Notre environnement est rempli de produits chimiques qui profitent \u00e0 notre mode de vie moderne. Cependant, ces produits chimiques peuvent interagir avec notre corps de mani\u00e8re inconnue ou difficile \u00e0 comprendre. En attendant, limiter son exposition \u00e0 ces deux insecticides semble \u00eatre un moyen important de maintenir un rythme circadien sain tout en r\u00e9duisant le risque de diab\u00e8te et d’autres maladies m\u00e9taboliques.<\/p>\n","protected":false},"excerpt":{"rendered":"

Il existe de nombreuses raisons de limiter son exposition aux insecticides. Selon une nouvelle \u00e9tude, l’interf\u00e9rence avec les voies de la m\u00e9latonine et un risque plus \u00e9lev\u00e9 de diab\u00e8te pourraient en faire partie. Que savez-vous des ingr\u00e9dients contenus dans vos insecticides pr\u00e9f\u00e9r\u00e9s ? Le carbaryl et le carbofuran sont des ingr\u00e9dients communs \u00e0 de nombreux […]<\/p>\n","protected":false},"author":15,"featured_media":25416,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[174,256,253,255,257],"tags":[],"class_list":{"0":"post-58489","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-le-rythme-circadien","8":"category-melatonine","9":"category-metabolisme","10":"category-sommeil","11":"category-travail-poste","12":"entry"},"acf":[],"yoast_head":"\nInsecticide Exposure: Creating Higher Risk for Diabetes<\/title>\n<meta name=\"description\" content=\"There are many reasons to limit your exposure to insecticides. 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