{"id":58457,"date":"2016-10-28T09:48:41","date_gmt":"2016-10-28T16:48:41","guid":{"rendered":"https:\/\/www.chronobiology.com\/reduction-oxygen-short-duration-may-reset-circadian-rhythm\/"},"modified":"2024-07-18T14:51:43","modified_gmt":"2024-07-18T21:51:43","slug":"la-r-duction-de-l-oxyg-ne-pendant-une-courte-dur-e-peut-r-initialiser-le-rythme-circadien","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/la-r-duction-de-l-oxyg-ne-pendant-une-courte-dur-e-peut-r-initialiser-le-rythme-circadien\/","title":{"rendered":"La r\u00e9duction de l’oxyg\u00e8ne pendant une courte dur\u00e9e peut r\u00e9initialiser le rythme circadien"},"content":{"rendered":"

R\u00e9duire l’oxyg\u00e8ne est g\u00e9n\u00e9ralement consid\u00e9r\u00e9 comme mauvais pour la sant\u00e9. Toutefois, de nouvelles recherches sugg\u00e8rent qu’une r\u00e9duction de l’oxyg\u00e8ne pendant une courte p\u00e9riode peut permettre de r\u00e9initialiser le rythme circadien.<\/p>\n

La plupart des gens ont souffert du d\u00e9calage horaire \u00e0 un moment ou \u00e0 un autre de leur vie. La cause du d\u00e9calage horaire est simple : Une perturbation du rythme circadien. La gu\u00e9rison du d\u00e9calage horaire est beaucoup plus complexe et n\u00e9cessite souvent des jours d’adaptation \u00e0 un nouveau cycle de sommeil et d’\u00e9veil. Toutefois, de nouvelles recherches dans le domaine de la chronobiologie sugg\u00e8rent qu’une r\u00e9duction de l’oxyg\u00e8ne pendant une courte p\u00e9riode peut r\u00e9initialiser le rythme circadien et gu\u00e9rir rapidement le d\u00e9calage horaire ainsi que d’autres troubles circadiens du sommeil.<\/p>\n

Quand les souris souffrent de d\u00e9calage horaire<\/h2>\n

Bien que les souris ne volent g\u00e9n\u00e9ralement pas d’un fuseau horaire \u00e0 l’autre, elles peuvent souffrir du d\u00e9calage horaire. Tout comme les humains, elles peuvent subir des changements dans leur environnement, comme l’heure d’\u00e9t\u00e9 et les horaires changeants des personnes qui s’occupent d’elles. Comme chez l’homme, le m\u00e9tabolisme des souris, notamment la quantit\u00e9 d’oxyg\u00e8ne qu’elles consomment, varie de mani\u00e8re pr\u00e9visible au cours d’une journ\u00e9e de 24 heures.<\/p>\n

Les sympt\u00f4mes que pr\u00e9sentent les souris souffrant de d\u00e9calage horaire semblent familiers \u00e0 tout \u00eatre humain ayant souffert de ce trouble : fatigue, baisse des fonctions cognitives et difficult\u00e9s \u00e0 dormir. Cependant, lorsque les souris sont soumises \u00e0 des niveaux plus faibles d’oxyg\u00e8ne dans l’air pendant une courte p\u00e9riode juste avant une perturbation importante de leur rythme circadien, elles semblent s’adapter presque imm\u00e9diatement sans aucun des effets secondaires communs au d\u00e9calage horaire<\/a>.<\/p>\n

HIF1\u03b1 et les besoins en oxyg\u00e8ne des cellules<\/h2>\n

Les chercheurs ont rapidement d\u00e9termin\u00e9 que la prot\u00e9ine HIF1\u03b1 \u00e9tait responsable de cette r\u00e9ponse aux environnements \u00e0 faible teneur en oxyg\u00e8ne. HIF1\u03b1 est une prot\u00e9ine qui indique aux cellules comment utiliser l’oxyg\u00e8ne et m\u00eame en quelle quantit\u00e9. Elle semble \u00e9galement \u00eatre impliqu\u00e9e dans une vari\u00e9t\u00e9 d’autres processus cellulaires, dont beaucoup d\u00e9pendent de l’oxyg\u00e8ne. Les souris dont le g\u00e8ne de cette prot\u00e9ine \u00e9tait d\u00e9sactiv\u00e9 n’ont pas r\u00e9agi aux changements des niveaux d’oxyg\u00e8ne par une r\u00e9initialisation du rythme circadien comme l’ont fait les souris pleinement fonctionnelles.<\/p>\n

De faibles niveaux d’oxyg\u00e8ne pourraient-ils r\u00e9initialiser le rythme circadien chez l’homme ?<\/h2>\n

La vie humaine est g\u00e9n\u00e9ralement plus complexe que celle des souris. Nous souffrons de divers troubles du rythme circadien, du d\u00e9calage horaire aux probl\u00e8mes li\u00e9s au travail post\u00e9. Un rythme circadien perturb\u00e9 a \u00e9t\u00e9 associ\u00e9 \u00e0 des maladies allant du diab\u00e8te de type 2 aux maladies cardiaques. En outre, le d\u00e9calage horaire peut \u00eatre source d’inconfort car les gens doivent passer des jours \u00e0 s’adapter \u00e0 des changements similaires \u00e0 ceux de l’horaire de travail et m\u00eame de l’heure d’\u00e9t\u00e9<\/a>.<\/p>\n

Cette prot\u00e9ine<\/a> \u00e9tant \u00e9galement pr\u00e9sente chez<\/a> l’homme, elle pourrait avoir d’\u00e9normes r\u00e9percussions sur la sant\u00e9 humaine. Les gens pourraient \u00eatre en mesure de porter un masque facial et de respirer de l’air \u00e0 faible teneur en oxyg\u00e8ne pendant quelques minutes seulement, pas assez longtemps pour causer des probl\u00e8mes de sant\u00e9, et de r\u00e9initialiser ainsi leur rythme circadien.<\/p>\n

N’essayez pas cela chez vous<\/h2>\n

Bien que les recherches soient prometteuses, il est important de ne pas essayer ce rem\u00e8de \u00e0 la maison. Le manque d’oxyg\u00e8ne peut \u00eatre dangereux s’il n’est pas soigneusement programm\u00e9 et planifi\u00e9. Tant que les scientifiques n’auront pas mis au point un moyen de rendre cette m\u00e9thode s\u00fbre et accessible au public, les gens devraient s’en tenir \u00e0 des rem\u00e8des dont l’utilit\u00e9 a \u00e9t\u00e9 prouv\u00e9e, comme la m\u00e9latonine<\/a>, la luminoth\u00e9rapie et d’autres moyens s\u00fbrs de r\u00e9initialiser le rythme circadien.<\/p>\n","protected":false},"excerpt":{"rendered":"

R\u00e9duire l’oxyg\u00e8ne est g\u00e9n\u00e9ralement consid\u00e9r\u00e9 comme mauvais pour la sant\u00e9. Toutefois, de nouvelles recherches sugg\u00e8rent qu’une r\u00e9duction de l’oxyg\u00e8ne pendant une courte p\u00e9riode peut permettre de r\u00e9initialiser le rythme circadien. La plupart des gens ont souffert du d\u00e9calage horaire \u00e0 un moment ou \u00e0 un autre de leur vie. La cause du d\u00e9calage horaire est […]<\/p>\n","protected":false},"author":15,"featured_media":24776,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[174,256,251],"tags":[],"class_list":{"0":"post-58457","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-le-rythme-circadien","8":"category-melatonine","9":"category-therapie-par-la-lumiere","10":"entry"},"acf":[],"yoast_head":"\nReduction of Oxygen for a Short Duration May Reset Circadian Rhythm<\/title>\n<meta name=\"description\" content=\"Reducing oxygen is generally considered bad for the health. However, new research suggests that doing so for a short period of time may reset one\u2019s circadian rhythm.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dev.chronobiology.com\/fr\/la-r-duction-de-l-oxyg-ne-pendant-une-courte-dur-e-peut-r-initialiser-le-rythme-circadien\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La r\u00e9duction de l'oxyg\u00e8ne pendant une courte dur\u00e9e peut r\u00e9initialiser le rythme circadien\" \/>\n<meta property=\"og:description\" content=\"Reducing oxygen is generally considered bad for the health. 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