{"id":58445,"date":"2016-09-23T10:56:39","date_gmt":"2016-09-23T17:56:39","guid":{"rendered":"https:\/\/www.chronobiology.com\/studies-show-melatonin-plays-important-role-multiple-sclerosis\/"},"modified":"2024-07-18T14:51:29","modified_gmt":"2024-07-18T21:51:29","slug":"des-tudes-montrent-que-la-m-latonine-joue-un-r-le-important-dans-la-scl-rose-en-plaques","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/des-tudes-montrent-que-la-m-latonine-joue-un-r-le-important-dans-la-scl-rose-en-plaques\/","title":{"rendered":"Des \u00e9tudes montrent que la m\u00e9latonine joue un r\u00f4le important dans la scl\u00e9rose en plaques"},"content":{"rendered":"

La recherche sugg\u00e8re que la m\u00e9latonine pourrait jouer un r\u00f4le important dans le processus et le traitement de maladies graves telles que la scl\u00e9rose en plaques.<\/p>\n

La scl\u00e9rose en plaques est fr\u00e9quente aux \u00c9tats-Unis et dans les pays d’Europe du Nord. Alors que ce diagnostic \u00e9tait autrefois presque une condamnation \u00e0 mort, de nouveaux m\u00e9dicaments et traitements permettent aux personnes atteintes de cette maladie et d’autres maladies auto-immunes de vivre plus longtemps et en meilleure sant\u00e9. Selon de nouvelles \u00e9tudes sur la scl\u00e9rose en plaques et la m\u00e9latonine<\/a>, le maintien d’un bon sommeil et de niveaux de m\u00e9latonine sains pourrait \u00eatre particuli\u00e8rement important dans la gestion de cette maladie.<\/p>\n

Qu’est-ce que la scl\u00e9rose en plaques ?<\/h2>\n

\"Studies<\/a>La scl\u00e9rose en plaques, \u00e9galement connue sous le nom de SEP, est une maladie auto-immune dans laquelle le syst\u00e8me immunitaire de l’organisme attaque la my\u00e9line, une substance semblable au cholest\u00e9rol qui isole les nerfs afin qu’ils puissent transmettre des impulsions \u00e0 une vitesse rapide. Sans cette isolation, les personnes atteintes de scl\u00e9rose en plaques peuvent souffrir de probl\u00e8mes de mouvement, d’\u00e9quilibre, de vision, de contr\u00f4le des intestins et de la vessie, etc. Elles peuvent \u00e9galement ressentir de la faiblesse, de la fatigue, des douleurs chroniques et d’autres sympt\u00f4mes d\u00e9bilitants. Si certaines personnes finissent par mourir de la maladie, beaucoup peuvent mener une vie relativement normale gr\u00e2ce aux traitements modernes.<\/p>\n

Les experts ne comprennent pas exactement les causes de la scl\u00e9rose en plaques, mais il existe quelques points communs. La plupart des personnes atteintes de scl\u00e9rose en plaques commencent \u00e0 pr\u00e9senter des sympt\u00f4mes entre 20 et 40 ans. La scl\u00e9rose en plaques est beaucoup plus fr\u00e9quente chez les femmes que chez les hommes. Les infections virales semblent souvent d\u00e9clencher le d\u00e9but et les rechutes de la scl\u00e9rose en plaques. Enfin, les personnes qui d\u00e9veloppent cette maladie sont plus susceptibles de vivre sous des latitudes septentrionales<\/a> avec moins de lumi\u00e8re, quelle que soit leur race ou leur appartenance ethnique.<\/p>\n

Sommeil, m\u00e9latonine et scl\u00e9rose en plaques<\/h2>\n

Quelle que soit la cause de la scl\u00e9rose en plaques, il semble qu’elle soit profond\u00e9ment li\u00e9e au sommeil. Plus de la moiti\u00e9 des personnes atteintes de scl\u00e9rose en plaques<\/a> pr\u00e9sentent un trouble du sommeil av\u00e9r\u00e9. Cela est d\u00fb en partie \u00e0 des probl\u00e8mes tels que la douleur chronique et la spasticit\u00e9 musculaire, qui peuvent interf\u00e9rer avec le repos. Cependant, la m\u00e9latonine semble \u00e9galement jouer un r\u00f4le important.<\/p>\n

De nombreuses personnes atteintes de SEP pr\u00e9sentent des taux extr\u00eamement bas de m\u00e9latonine et d’alpha-MSH<\/a>, l’hormone qui stimule la production de m\u00e9latonine. La pr\u00e9valence d’un faible taux de m\u00e9latonine chez les personnes souffrant de cette maladie a conduit certains scientifiques \u00e0 se demander si une d\u00e9faillance de la glande pin\u00e9ale, qui produit et stocke la m\u00e9latonine, ne serait pas l’un des facteurs cl\u00e9s de l’exacerbation des sympt\u00f4mes.<\/p>\n

Chronobiologie : Une future option th\u00e9rapeutique pour la SEP ?<\/h2>\n

Des \u00e9tudes r\u00e9centes sugg\u00e8rent que la m\u00e9latonine pourrait \u00eatre un traitement efficace pour lutter contre la scl\u00e9rose en plaques<\/a>. La m\u00e9latonine a un effet anti-inflammatoire qui peut contribuer \u00e0 r\u00e9duire les l\u00e9sions de la my\u00e9line dans le cerveau. En outre, la m\u00e9latonine peut contribuer \u00e0 r\u00e9guler l’activit\u00e9 de diff\u00e9rents types de cellules T<\/a>, qui jouent un r\u00f4le important dans le d\u00e9veloppement de cette maladie. Il existe deux types de cellules T : Les cellules T pathog\u00e8nes, qui attaquent les tissus, et les cellules T r\u00e9gulatrices, qui r\u00e9gulent et suppriment l’activit\u00e9 inutile des cellules T pathog\u00e8nes. Les personnes qui ont des taux \u00e9lev\u00e9s de m\u00e9latonine ont des taux plus \u00e9lev\u00e9s de cellules T r\u00e9gulatrices, ce qui peut contribuer \u00e0 pr\u00e9venir une grande partie des dommages associ\u00e9s \u00e0 la scl\u00e9rose en plaques. C’est peut-\u00eatre la raison pour laquelle les personnes atteintes de cette maladie pr\u00e9sentent souvent moins de pouss\u00e9es et de rechutes pendant les mois froids, lorsque la lumi\u00e8re est faible et que les niveaux de m\u00e9latonine sont \u00e9lev\u00e9s.<\/p>\n

La m\u00e9latonine pourrait-elle constituer une option th\u00e9rapeutique s\u00fbre et efficace pour la scl\u00e9rose en plaques ? Bien que des \u00e9tudes suppl\u00e9mentaires soient n\u00e9cessaires dans ce domaine, les donn\u00e9es sugg\u00e8rent que cette hormone pourrait \u00eatre utile \u00e0 de nombreuses personnes luttant contre cette maladie d\u00e9bilitante. La m\u00e9latonine ne se limite pas au sommeil<\/a> et joue divers r\u00f4les dans la sant\u00e9 humaine que nous commen\u00e7ons \u00e0 peine \u00e0 d\u00e9couvrir.<\/p>\n","protected":false},"excerpt":{"rendered":"

La recherche sugg\u00e8re que la m\u00e9latonine pourrait jouer un r\u00f4le important dans le processus et le traitement de maladies graves telles que la scl\u00e9rose en plaques. La scl\u00e9rose en plaques est fr\u00e9quente aux \u00c9tats-Unis et dans les pays d’Europe du Nord. Alors que ce diagnostic \u00e9tait autrefois presque une condamnation \u00e0 mort, de nouveaux m\u00e9dicaments […]<\/p>\n","protected":false},"author":15,"featured_media":24724,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[256,255],"tags":[],"class_list":{"0":"post-58445","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-melatonine","8":"category-sommeil","9":"entry"},"acf":[],"yoast_head":"\nStudies Show Melatonin Plays an Important Role in Multiple Sclerosis<\/title>\n<meta name=\"description\" content=\"New research suggests that melatonin may play an important role in the process and treatment of 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