{"id":58362,"date":"2016-04-08T11:40:55","date_gmt":"2016-04-08T18:40:55","guid":{"rendered":"https:\/\/www.chronobiology.com\/the-genetic-link-between-sleep-deprivation-and-metabolic-disorders-translin\/"},"modified":"2024-07-18T14:45:59","modified_gmt":"2024-07-18T21:45:59","slug":"lien-g-n-tique-entre-le-manque-de-sommeil-et-les-troubles-m-taboliques-translin","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/lien-g-n-tique-entre-le-manque-de-sommeil-et-les-troubles-m-taboliques-translin\/","title":{"rendered":"Lien g\u00e9n\u00e9tique entre le manque de sommeil et les troubles m\u00e9taboliques : Translin"},"content":{"rendered":"

Une nouvelle \u00e9tude a identifi\u00e9 le g\u00e8ne qui pourrait \u00eatre le cha\u00eenon manquant entre le manque de sommeil et les troubles m\u00e9taboliques.<\/p>\n

Les scientifiques savent depuis longtemps qu’il existe un lien entre le manque de sommeil et les troubles du syst\u00e8me m\u00e9tabolique<\/a> tels que l’ob\u00e9sit\u00e9 et le diab\u00e8te de type 2. Des \u00e9tudes ont montr\u00e9 que certaines personnes sont plus sensibles aux effets destructeurs du manque de sommeil sur le syst\u00e8me endocrinien. Comme les membres de certaines familles sont plus susceptibles de souffrir des effets m\u00e9taboliques du manque de sommeil, les chercheurs ont soup\u00e7onn\u00e9 une composante g\u00e9n\u00e9tique. Un g\u00e8ne r\u00e9cemment d\u00e9couvert, appel\u00e9 transline, est probablement le coupable.<\/p>\n

Sommeil et m\u00e9tabolisme<\/h2>\n

Il existe un lien \u00e9vident entre le sommeil et le m\u00e9tabolisme. Le manque de sommeil ralentit le m\u00e9tabolisme, le m\u00e9tabolisme du glucose<\/a>, la croissance cellulaire et la fatigue. Les troubles du m\u00e9tabolisme peuvent \u00e9galement affecter les habitudes de sommeil, la fatigue et l’insomnie \u00e9tant souvent les premiers sympt\u00f4mes de maladies telles que le diab\u00e8te et l’hypothyro\u00efdie. Votre m\u00e9tabolisme et vos habitudes de sommeil sont clairement li\u00e9s, mais comment ?<\/p>\n

Les mouches des fruits et le sommeil<\/h2>\n

Bien que les mouches \u00e0 fruits soient tr\u00e8s diff\u00e9rentes des humains, elles sont souvent utilis\u00e9es comme sujet de recherche en g\u00e9n\u00e9tique et en biologie mol\u00e9culaire<\/a>. Il y a plusieurs raisons \u00e0 cela. Leur g\u00e9nome – et donc leur d\u00e9veloppement – est similaire au n\u00f4tre, bien que nous devenions finalement des organismes tr\u00e8s diff\u00e9rents. En outre, les mouches des fruits ont un temps de g\u00e9n\u00e9ration court, de sorte que les chercheurs peuvent suivre les effets des changements g\u00e9n\u00e9tiques sur plusieurs g\u00e9n\u00e9rations en quelques semaines seulement. Les mouches \u00e0 fruits ont \u00e9galement des habitudes de sommeil similaires aux n\u00f4tres, ce qui explique pourquoi elles ont fait l’objet d’une r\u00e9cente \u00e9tude novatrice sur les troubles du sommeil et les habitudes alimentaires.<\/p>\n

Lorsque les mouches des fruits per\u00e7oivent qu’elles ont besoin de nourriture, le g\u00e8ne translin<\/a> cr\u00e9e des prot\u00e9ines qui les maintiennent \u00e9veill\u00e9es afin qu’elles puissent chercher de la nourriture. Chez les drosophiles pr\u00e9sentant une mutation de la transline, cet \u00e9tat d’\u00e9veil et cette faim persistent m\u00eame lorsque les mouches sont bien nourries. La transline est un g\u00e8ne hautement conserv\u00e9, ce qui signifie que des animaux plus complexes tels que l’homme le poss\u00e8dent \u00e9galement.<\/p>\n

La poule ou l’\u0153uf ?<\/h2>\n

\"The<\/a>Les chercheurs soup\u00e7onnent depuis longtemps le manque de sommeil d’\u00eatre \u00e0 l’origine de troubles de l’alimentation et du m\u00e9tabolisme. De nombreuses recherches confirment cette hypoth\u00e8se. M\u00eame si cela reste vrai, la nouvelle \u00e9tude sur les mouches des fruits sugg\u00e8re qu’un troisi\u00e8me facteur g\u00e9n\u00e9tique est \u00e0 l’origine de l’insomnie et de la suralimentation. Cette d\u00e9couverte est importante, car notre capacit\u00e9 \u00e0 traiter les mutations g\u00e9n\u00e9tiques s’accro\u00eet de jour en jour. En outre, les chercheurs pourraient \u00eatre en mesure d’identifier les prot\u00e9ines produites par la transline et de cr\u00e9er un m\u00e9dicament qui contrecarre leurs effets. Une chose est s\u00fbre : l ‘homme et la mouche \u00e0 fruits ont tous deux tendance \u00e0 grignoter au lieu de dormir<\/a>, ce qui entra\u00eene une prise de poids et un manque de sommeil.<\/p>\n

Les troubles du sommeil peuvent affecter presque tous les aspects de notre vie, de notre niveau d’\u00e9nergie \u00e0 notre sant\u00e9 mentale<\/a> et m\u00eame au risque de sant\u00e9 cardiovasculaire. Les troubles m\u00e9taboliques peuvent avoir un impact tout aussi important sur la sant\u00e9 et le bien-\u00eatre. Ce g\u00e8ne permet de mieux comprendre ces deux types de maladies, ce qui, esp\u00e9rons-le, permettra aux gens d’obtenir le traitement dont ils ont besoin pour vivre heureux, en bonne sant\u00e9 et bien repos\u00e9s.<\/p>\n","protected":false},"excerpt":{"rendered":"

Une nouvelle \u00e9tude a identifi\u00e9 le g\u00e8ne qui pourrait \u00eatre le cha\u00eenon manquant entre le manque de sommeil et les troubles m\u00e9taboliques. Les scientifiques savent depuis longtemps qu’il existe un lien entre le manque de sommeil et les troubles du syst\u00e8me m\u00e9tabolique tels que l’ob\u00e9sit\u00e9 et le diab\u00e8te de type 2. Des \u00e9tudes ont montr\u00e9 […]<\/p>\n","protected":false},"author":15,"featured_media":24312,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[174,253,255],"tags":[],"class_list":{"0":"post-58362","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-le-rythme-circadien","8":"category-metabolisme","9":"category-sommeil","10":"entry"},"acf":[],"yoast_head":"\nLien g\u00e9n\u00e9tique entre le manque de sommeil et les troubles m\u00e9taboliques : Translin – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"A new study has identified the gene that may be the missing link between sleep 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