{"id":58346,"date":"2016-03-03T11:59:13","date_gmt":"2016-03-03T19:59:13","guid":{"rendered":"https:\/\/www.chronobiology.com\/the-missing-link-between-mood-sleep-the-per3-gene\/"},"modified":"2024-07-18T14:45:40","modified_gmt":"2024-07-18T21:45:40","slug":"le-cha-non-manquant-entre-l-humeur-et-le-sommeil-le-g-ne-per3","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/le-cha-non-manquant-entre-l-humeur-et-le-sommeil-le-g-ne-per3\/","title":{"rendered":"Le cha\u00eenon manquant entre l’humeur et le sommeil : Le g\u00e8ne PER3"},"content":{"rendered":"

Avez-vous du mal \u00e0 rester de bonne humeur lorsque vous n’avez pas bien dormi ? Le g\u00e8ne du rythme circadien PER3 a r\u00e9cemment \u00e9t\u00e9 identifi\u00e9 comme le lien entre le sommeil et l’humeur.<\/p>\n

L’un des sympt\u00f4mes les plus visibles d’une nuit blanche est un changement d’humeur<\/a>. Les enfants en bas \u00e2ge ne sont pas les seuls \u00e0 devenir trop \u00e9motifs lorsqu’ils ne font pas leur sieste r\u00e9guli\u00e8re ; m\u00eame l’adulte le plus stable se sentira d\u00e9prim\u00e9, en col\u00e8re ou tout simplement moins stable \u00e9motionnellement lorsqu’il ne dort pas assez. En outre, certaines maladies mentales, telles que le trouble bipolaire<\/a> et la schizophr\u00e9nie, ont \u00e9t\u00e9 associ\u00e9es \u00e0 des troubles du sommeil. Si les m\u00e9decins et les scientifiques reconnaissent depuis longtemps le lien entre le sommeil et la sant\u00e9 \u00e9motionnelle, ils n’ont d\u00e9couvert que r\u00e9cemment la base biologique de ce lien : un g\u00e8ne de l’horloge tr\u00e8s \u00e9tudi\u00e9.<\/p>\n

Chronobiologie, sommeil et sant\u00e9 \u00e9motionnelle<\/h2>\n

De nombreuses personnes consid\u00e8rent le sommeil comme une perte de temps, m\u00eame s’il est biologiquement n\u00e9cessaire. Cependant, le sommeil n’est pas un temps de repos inerte. M\u00eame si vous n’\u00eates pas conscient lorsque vous dormez, votre corps et votre cerveau sont tr\u00e8s occup\u00e9s. L’une des activit\u00e9s les plus importantes du sommeil est l’\u00e9limination des d\u00e9chets et la r\u00e9paration des l\u00e9sions cellulaires du cerveau. Votre cerveau ne peut pas effectuer ces t\u00e2ches essentielles aussi efficacement lorsque vous \u00eates conscient.<\/p>\n

Lorsque les gens ne b\u00e9n\u00e9ficient pas d’un sommeil de qualit\u00e9 suffisant, leur humeur est souvent la premi\u00e8re \u00e0 en souffrir. Apr\u00e8s une seule nuit sans sommeil, les gens sont plus r\u00e9actifs sur le plan \u00e9motionnel. Ils peuvent avoir du mal \u00e0 contr\u00f4ler leurs \u00e9motions et sont g\u00e9n\u00e9ralement de mauvaise humeur. En cas de manque chronique de sommeil, les personnes sont beaucoup plus sujettes \u00e0 la d\u00e9pression et \u00e0 l’anxi\u00e9t\u00e9, ainsi qu’\u00e0 une baisse des fonctions cognitives et \u00e0 des pertes de m\u00e9moire. On a m\u00eame constat\u00e9 qu’un manque de sommeil de qualit\u00e9 contribuait \u00e0 des maladies mentales graves<\/a>.<\/p>\n

Le lien entre l’humeur et le g\u00e8ne PER3<\/h2>\n

\"The<\/a>Le g\u00e8ne PER3<\/a> est connu depuis longtemps comme un \u00e9l\u00e9ment important du rythme circadien humain. Ce g\u00e8ne s’exprime principalement dans le noyau suprachiasmatique de l’hypothalamus, qui est le centre c\u00e9r\u00e9bral associ\u00e9 au rythme circadien des mammif\u00e8res. Dans une \u00e9tude r\u00e9cente portant sur des personnes souffrant \u00e0 la fois de troubles de l’humeur et de troubles du sommeil<\/a>, ce g\u00e8ne s’est r\u00e9v\u00e9l\u00e9 \u00eatre le lien commun. Les chercheurs ont ensuite \u00e9lev\u00e9 des souris pr\u00e9sentant une mutation g\u00e9n\u00e9tique similaire et ont d\u00e9couvert que ces souris pr\u00e9sentaient des signes de troubles de l’humeur tels que la d\u00e9pression et le trouble affectif saisonnier, en plus des perturbations attendues du rythme circadien.<\/p>\n

Comme les souris \u00e9taient par ailleurs en bonne sant\u00e9 et g\u00e9n\u00e9tiquement normales, PER3 semble contribuer de mani\u00e8re significative \u00e0 la fois \u00e0 la sant\u00e9 mentale et aux cycles du sommeil. Les chercheurs pensent que le maintien d’un rythme circadien sain, qui est difficile lorsque d’importants g\u00e8nes de synchronisation fonctionnent mal, constitue une protection contre les troubles mentaux. Lorsque ce g\u00e8ne ne fonctionne pas, les personnes sont plus susceptibles d’\u00eatre affect\u00e9es \u00e9motionnellement par des changements dans leur environnement.<\/p>\n

Le besoin de sommeil est inscrit dans les g\u00e8nes<\/h2>\n

Il n’existe actuellement aucun moyen de corriger la plupart des troubles g\u00e9n\u00e9tiques. Toutefois, les personnes qui ont des probl\u00e8mes d’humeur peuvent constater que leurs sympt\u00f4mes s’am\u00e9liorent en prenant des mesures pour maintenir des habitudes de sommeil saines. Il est souvent difficile pour les personnes souffrant de d\u00e9pression ou de troubles affectifs saisonniers de dormir suffisamment, mais les suppl\u00e9ments de m\u00e9latonine, la luminoth\u00e9rapie et une bonne hygi\u00e8ne de sommeil peuvent les aider. Cette \u00e9tude et plusieurs autres \u00e9tudes r\u00e9centes sur le lien entre les maladies mentales et le rythme circadien sugg\u00e8rent que le sommeil est un \u00e9l\u00e9ment important de la sant\u00e9 \u00e9motionnelle et physique.<\/p>\n

Les gens d’aujourd’hui ont du mal \u00e0 trouver un sommeil de qualit\u00e9 en quantit\u00e9 suffisante et \u00e0 maintenir un rythme quotidien stable. Cela peut nous perturber, au sens propre comme au sens figur\u00e9. Un sommeil ad\u00e9quat est un \u00e9l\u00e9ment important d’un mode de vie sain et devrait \u00eatre une priorit\u00e9 pour les personnes souffrant de troubles de l’humeur.<\/p>\n","protected":false},"excerpt":{"rendered":"

Avez-vous du mal \u00e0 rester de bonne humeur lorsque vous n’avez pas bien dormi ? Le g\u00e8ne du rythme circadien PER3 a r\u00e9cemment \u00e9t\u00e9 identifi\u00e9 comme le lien entre le sommeil et l’humeur. L’un des sympt\u00f4mes les plus visibles d’une nuit blanche est un changement d’humeur. Les enfants en bas \u00e2ge ne sont pas les […]<\/p>\n","protected":false},"author":15,"featured_media":24252,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[174,259,255],"tags":[],"class_list":{"0":"post-58346","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-le-rythme-circadien","8":"category-sante-mentale","9":"category-sommeil","10":"entry"},"acf":[],"yoast_head":"\nLe cha\u00eenon manquant entre l'humeur et le sommeil : Le g\u00e8ne PER3 – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"Do you struggle to keep a good mood when you haven't slept well? 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The PER3 circadian rhythm gene has been recently identified as the link between sleep and mood.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dev.chronobiology.com\/fr\/le-cha-non-manquant-entre-l-humeur-et-le-sommeil-le-g-ne-per3\/\" \/>\n<meta property=\"og:site_name\" content=\"Chronobiology.com\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/chronobiology\" \/>\n<meta property=\"article:published_time\" content=\"2016-03-03T19:59:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-18T21:45:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/dev.chronobiology.com\/wp-content\/uploads\/2016\/02\/the-missing-link-between-mood-sleep-the-per3-gene-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1800\" \/>\n\t<meta property=\"og:image:height\" content=\"679\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Edwin Urbina\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"The Missing Link Between Mood & Sleep: The PER3 Gene\" \/>\n<meta name=\"twitter:description\" content=\"Do you struggle to keep a good mood when you haven't slept well? 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