{"id":58248,"date":"2015-08-14T20:13:44","date_gmt":"2015-08-14T20:13:44","guid":{"rendered":"https:\/\/www.chronobiology.com\/wonder-hormone-improves-outcomes-in-cancer-patients\/"},"modified":"2024-07-18T14:43:43","modified_gmt":"2024-07-18T21:43:43","slug":"l-hormone-miracle-am-liore-les-r-sultats-chez-les-patients-atteints-de-cancer","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/l-hormone-miracle-am-liore-les-r-sultats-chez-les-patients-atteints-de-cancer\/","title":{"rendered":"L’hormone miracle am\u00e9liore les r\u00e9sultats chez les patients atteints de cancer"},"content":{"rendered":"

La recherche sur le cancer a d\u00e9bouch\u00e9 sur de nombreux traitements nouveaux et passionnants qui am\u00e9liorent les r\u00e9sultats en s’attaquant aux processus biochimiques sous-jacents \u00e0 cette maladie grave. Si la m\u00e9latonine <\/a>est utilis\u00e9e depuis des d\u00e9cennies pour traiter l’insomnie et d’autres troubles du sommeil, elle pourrait \u00e9galement constituer un traitement pr\u00e9cieux contre le cancer. De nouvelles \u00e9tudes sugg\u00e8rent que la m\u00e9latonine inhibe la croissance des tumeurs tout en att\u00e9nuant les effets secondaires d’autres traitements anticanc\u00e9reux.<\/p>\n

La m\u00e9latonine : l’ultime multit\u00e2che<\/h2>\n

La m\u00e9latonine est l’une des hormones les plus actives du corps humain, car elle agit sur toute une s\u00e9rie de processus cellulaires vitaux<\/a>. Elle contribue \u00e0 la r\u00e9paration cellulaire, incite les cellules \u00e0 lib\u00e9rer diff\u00e9rentes hormones en fonction des besoins et favorise un rythme circadien<\/a> sain, c’est-\u00e0-dire une horloge interne de 24 heures. De faibles niveaux de m\u00e9latonine ont \u00e9t\u00e9 associ\u00e9s \u00e0 des maladies aussi diverses que le cancer, les maladies neurod\u00e9g\u00e9n\u00e9ratives et m\u00eame les crises cardiaques.<\/p>\n

Avec l’\u00e2ge, les niveaux de m\u00e9latonine diminuent et l’incidence de nombreuses maladies augmente. S’agit-il d’une co\u00efncidence ? De nouvelles \u00e9tudes montrent qu’un faible taux de m\u00e9latonine contribue en fait \u00e0 de nombreuses maladies associ\u00e9es au vieillissement et qu’une suppl\u00e9mentation en m\u00e9latonine peut constituer un traitement pr\u00e9ventif efficace<\/a>.<\/p>\n

M\u00e9latonine et cancer<\/h2>\n

L’\u00e2ge n’est pas la seule cause d’un faible taux de m\u00e9latonine. Lorsque les gens manquent chroniquement de sommeil, comme c’est souvent le cas dans la soci\u00e9t\u00e9 moderne, leur taux de m\u00e9latonine diminue et fluctue davantage. Les personnes qui ne sont pas en mesure de dormir des heures normales la nuit courent un risque plus \u00e9lev\u00e9 de cancer<\/a>, raison pour laquelle l’Organisation mondiale de la sant\u00e9 consid\u00e8re le travail post\u00e9 comme un agent canc\u00e9rig\u00e8ne.<\/p>\n

Bien que le lien entre le d\u00e9r\u00e8glement du rythme circadien et le cancer soit clair, le m\u00e9canisme de ce risque accru de cancer \u00e9tait jusqu’\u00e0 pr\u00e9sent inconnu. Cependant, une nouvelle m\u00e9ta-analyse d’\u00e9tudes chronobiologiques <\/a>sugg\u00e8re que la m\u00e9latonine attaque le cancer \u00e0 sa base m\u00eame, en perturbant les processus biochimiques par lesquels les tumeurs se d\u00e9veloppent.<\/p>\n

La m\u00e9latonine pourrait-elle \u00eatre le prochain grand traitement contre le cancer ?<\/h2>\n

\"Wonder<\/a>Une m\u00e9ta-\u00e9tude en chronobiologie<\/a> a examin\u00e9 les recherches ant\u00e9rieures sur la m\u00e9latonine et a dress\u00e9 une longue liste d’effets anticanc\u00e9reux. La m\u00e9latonine peut emp\u00eacher les cellules canc\u00e9reuses de prolif\u00e9rer en d\u00e9clenchant l’apoptose (ou mort cellulaire programm\u00e9e) et en coupant l’approvisionnement en sang des tumeurs. En outre, la m\u00e9latonine est d\u00e9j\u00e0 connue pour agir comme antioxydant et pour am\u00e9liorer le syst\u00e8me immunitaire, ce qui emp\u00eache le cancer de se d\u00e9velopper. Enfin, un faible taux de m\u00e9latonine peut entra\u00eener des niveaux \u00e9lev\u00e9s de cytokines, une mol\u00e9cule naturelle li\u00e9e au cancer.<\/p>\n

Lorsque des animaux de laboratoire atteints de tumeurs re\u00e7oivent de la m\u00e9latonine, la croissance de la tumeur est consid\u00e9rablement ralentie. En outre, des \u00e9tudes montrent que les patients humains atteints de cancer tol\u00e8rent mieux les autres traitements lorsqu’ils prennent un suppl\u00e9ment de m\u00e9latonine. Dans un avenir proche, la m\u00e9latonine pourrait faire partie d’un traitement standard contre le cancer.<\/p>\n

Les chercheurs en chronobiologie et dans divers domaines reconnaissent que la m\u00e9latonine est prometteuse tant pour la pr\u00e9vention que pour le traitement du cancer. Cependant, il reste difficile d’obtenir un financement pour les \u00e9tudes dans ce domaine. Aux \u00c9tats-Unis, de nombreuses \u00e9tudes sont men\u00e9es par des entreprises d\u00e9sireuses de tirer profit des nouvelles d\u00e9couvertes. La m\u00e9latonine \u00e9tant d\u00e9j\u00e0 largement disponible et abordable, il n’y a pas d’incitation financi\u00e8re \u00e0 l’\u00e9tudier. N\u00e9anmoins, un nombre important et croissant d’\u00e9tudes sur cette hormone multit\u00e2che sont en cours, et de nouvelles d\u00e9couvertes sur le lien entre le rythme circadien et la sant\u00e9 sont annonc\u00e9es presque chaque semaine.<\/p>\n","protected":false},"excerpt":{"rendered":"

La recherche sur le cancer a d\u00e9bouch\u00e9 sur de nombreux traitements nouveaux et passionnants qui am\u00e9liorent les r\u00e9sultats en s’attaquant aux processus biochimiques sous-jacents \u00e0 cette maladie grave. Si la m\u00e9latonine est utilis\u00e9e depuis des d\u00e9cennies pour traiter l’insomnie et d’autres troubles du sommeil, elle pourrait \u00e9galement constituer un traitement pr\u00e9cieux contre le cancer. De […]<\/p>\n","protected":false},"author":15,"featured_media":23720,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[256,241,242,255,257],"tags":[],"class_list":{"0":"post-58248","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-melatonine","8":"category-recherche-sur-le-cancer","9":"category-sante-des-cellules","10":"category-sommeil","11":"category-travail-poste","12":"entry"},"acf":[],"yoast_head":"\nL'hormone miracle am\u00e9liore les r\u00e9sultats chez les patients atteints de cancer – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"Cancer research has yielded many new and exciting treatments that improve outcomes by attacking the biochemical processes underlying this serious disease. 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