{"id":58142,"date":"2015-01-12T20:09:08","date_gmt":"2015-01-12T20:09:08","guid":{"rendered":"https:\/\/www.chronobiology.com\/how-chronobiology-is-impacting-alzheimers-and-dementia-treatment\/"},"modified":"2024-07-18T14:40:38","modified_gmt":"2024-07-18T21:40:38","slug":"l-impact-de-la-chronobiologie-sur-le-traitement-de-la-maladie-d-alzheimer-et-de-la-d-mence","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/fr\/l-impact-de-la-chronobiologie-sur-le-traitement-de-la-maladie-d-alzheimer-et-de-la-d-mence\/","title":{"rendered":"L’impact de la chronobiologie sur le traitement de la maladie d’Alzheimer et de la d\u00e9mence"},"content":{"rendered":"

Chronobiologie : Une science r\u00e9volutionnaire<\/h2>\n

Lachronobiologie<\/a> \u00e9tudie les horloges internes dont nous disposons et dont nous avons besoin pour r\u00e9guler des processus importants tels que la division cellulaire, la prolif\u00e9ration de la peau et la production de m\u00e9latonine, pour n’en citer que quelques-uns. Pour commencer \u00e0 comprendre la chronobiologie, pensez \u00e0 vos propres rythmes de base. Le moment de la journ\u00e9e le plus propice \u00e0 l’\u00e9tude d’un nouveau sujet, par exemple, peut \u00eatre le r\u00e9veil pour certains, mais pour d’autres, c’est le d\u00e9but de la soir\u00e9e qui convient le mieux. Le terme \u00ab\u00a0horloge biologique\u00a0\u00bb a c\u00e9d\u00e9 la place au sens plus large de chronobiologie, ce qui a eu pour effet de d\u00e9placer le centre d’int\u00e9r\u00eat de l’\u00e9tude des individus vers des segments entiers de l’existence humaine. Les personnes \u00e2g\u00e9es, en particulier les plus fragiles d’entre nous, ont besoin que ce domaine critique<\/a> soit explor\u00e9 en profondeur, document\u00e9 et utilis\u00e9 pour le traitement de leurs troubles tels que la maladie d’Alzheimer et la d\u00e9mence.<\/p>\n

Chronobiologie et soins<\/h2>\n

\"Chronobiology,<\/a>Lorsqu’une personne \u00e2g\u00e9e consomme un m\u00e9dicament \u00e0 un moment de la journ\u00e9e qui n’est pas adapt\u00e9 \u00e0 son m\u00e9tabolisme, elle ne b\u00e9n\u00e9ficie pas de l’effet complet du m\u00e9dicament et peut m\u00eame le gaspiller compl\u00e8tement. M\u00eame si l’effet du m\u00e9dicament n’est pas annul\u00e9, mais simplement diminu\u00e9, des troubles aussi graves que la maladie d’Alzheimer et la d\u00e9mence exigent le plus grand effort de la part des m\u00e9decins, des infirmi\u00e8res et des aides-soignantes dipl\u00f4m\u00e9es pour maintenir le niveau \u00e9lev\u00e9 de soins que nos a\u00een\u00e9s m\u00e9ritent. Une approche holistique implique une synergie d’observations sur le patient concernant le type et le degr\u00e9 de d\u00e9mence ou le stade de la maladie d’Alzheimer dont il est atteint. Et tout comme il est important de comprendre le stade d’une maladie pour d\u00e9terminer le m\u00e9dicament appropri\u00e9, il est important de d\u00e9couvrir \u00e0 quel moment de la journ\u00e9e les rythmes internes du corps d’un patient absorberont le mieux ce m\u00e9dicament. C’est ce que les chronobiologistes du monde entier tentent de d\u00e9terminer.<\/p>\n

Le cr\u00e9puscule<\/h2>\n

\"Chronobiology,<\/a>Le cr\u00e9puscule<\/a>, l’agitation dont souffrent de nombreuses personnes atteintes de la maladie d’Alzheimer et de la d\u00e9mence, signifie que le rythme circadien<\/a> est perturb\u00e9 par rapport \u00e0 son activit\u00e9 normale pendant la journ\u00e9e et \u00e0 son repos pendant la nuit. La fin de l’apr\u00e8s-midi, avec ses ombres qui s’allongent, peut provoquer la confusion chez le patient, qui peut r\u00e9agir en errant, en criant ou en devenant combatif. Il va sans dire que la pression exerc\u00e9e sur les soignants est extr\u00eame, tout comme le danger concomitant pour les patients \u00e2g\u00e9s vivant \u00e0 domicile s’ils se blessent ou se perdent. L’objectif du m\u00e9decin est d’att\u00e9nuer les effets du syndrome du cr\u00e9puscule en programmant une m\u00e9dication qui profite au patient lorsque l’environnement qui l’entoure l’expose au risque le plus \u00e9lev\u00e9, et la compr\u00e9hension des cycles internes et externes est l’un des principaux axes de la chronobiologie.<\/p>\n

Le changement est l’ennemi<\/h2>\n

\"Chronobiology,<\/a>\u00c0 domicile ou en institution, le patient \u00e2g\u00e9 r\u00e9siste au changement. Le soignant avis\u00e9 sait que minimiser les chocs mentaux subis par les personnes dont il a la charge est aussi dans son int\u00e9r\u00eat, et applique donc les m\u00e9dicaments prescrits selon un calendrier strict. Tout comme \u00e0 l’autre extr\u00e9mit\u00e9 du spectre de la vie, la petite enfance, un horaire r\u00e9gulier pour les personnes \u00e2g\u00e9es favorise le d\u00e9veloppement d’un rythme qui les maintient aussi calmes et confortables que possible. Pour les personnes atteintes de la maladie d’Alzheimer ou de d\u00e9mence, un simple changement de personnel soignant peut entra\u00eener une perturbation des facult\u00e9s mentales. La programmation de la m\u00e9latonine<\/a>, un somnif\u00e8re, avant le coucher et la luminoth\u00e9rapie t\u00f4t le matin sont des exemples de l’utilisation de la chronobiologie dans les soins aux patients atteints de la maladie d’Alzheimer ou d’une d\u00e9mence.<\/p>\n

L’avenir de la chronobiologie et de la maladie d’Alzheimer<\/h2>\n

Les rythmes circadiens n\u00e9cessaires \u00e0 des nuits r\u00e9guli\u00e8res et paisibles, remplies d’un sommeil r\u00e9g\u00e9n\u00e9rateur, sont perturb\u00e9s parce que les patients atteints de la maladie d’Alzheimer ou de d\u00e9mence ne re\u00e7oivent pas le stimulus d’un Zeitgeber, comme une lumi\u00e8re vive, au moment et de la mani\u00e8re appropri\u00e9s. La lumi\u00e8re du jour est le rep\u00e8re temporel connu le plus fort chez l’homme. L’avenir de la chronobiologie dans le traitement de la maladie d’Alzheimer et de la d\u00e9mence est prometteur si elle continue \u00e0 d\u00e9velopper le traitement par la lumi\u00e8re, les aides au sommeil, la stimulation sociale et l’administration de m\u00e9dicaments aux patients en fonction de l’heure d’application la plus efficace de chaque m\u00e9dicament.<\/p>\n","protected":false},"excerpt":{"rendered":"

Chronobiologie : Une science r\u00e9volutionnaire Lachronobiologie \u00e9tudie les horloges internes dont nous disposons et dont nous avons besoin pour r\u00e9guler des processus importants tels que la division cellulaire, la prolif\u00e9ration de la peau et la production de m\u00e9latonine, pour n’en citer que quelques-uns. Pour commencer \u00e0 comprendre la chronobiologie, pensez \u00e0 vos propres rythmes de […]<\/p>\n","protected":false},"author":11,"featured_media":22992,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[174,259,255],"tags":[],"class_list":{"0":"post-58142","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-le-rythme-circadien","8":"category-sante-mentale","9":"category-sommeil","10":"entry"},"acf":[],"yoast_head":"\nL'impact de la chronobiologie sur le traitement de la maladie d'Alzheimer et de la d\u00e9mence – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"The term 'body clock' has given way to the broader sense of chronobiology, changing the emphasis of study from individuals to entire segments within the human range of existence. 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