{"id":18949,"date":"2017-01-30T14:36:38","date_gmt":"2017-01-30T22:36:38","guid":{"rendered":"https:\/\/www.chronobiology.com\/histoire\/"},"modified":"2020-06-18T07:53:51","modified_gmt":"2020-06-18T14:53:51","slug":"histoire","status":"publish","type":"page","link":"https:\/\/dev.chronobiology.com\/fr\/melatonine-chronobiologie\/histoire\/","title":{"rendered":"Histoire"},"content":{"rendered":"

[vc_row full_width=\u00a0\u00bbstretch_row\u00a0\u00bb el_class=\u00a0\u00bbbanner-top\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00a0\u00bb][vc_column][vc_custom_heading source=\u00a0\u00bbpost_title\u00a0\u00bb font_container=\u00a0\u00bbtag:h1|text_align:center\u00a0\u00bb use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00a0\u00bbmelatoninfacts2″][vc_column width=\u00a0\u00bb3\/4″][vc_column_text]<\/p>\n

Historie<\/h2>\n

La m\u00e9latonine est une hormone secr\u00e9t\u00e9e par la glande pin\u00e9ale (glandula pinealis), un organe d\u00e9j\u00e0 mentionn\u00e9 par Galien de Pergame et autres \u00e9minences grecques au IIe si\u00e8cle. Au XVIe si\u00e8cle, le philosophe et scientifique fran\u00e7ais Descartes, d\u00e9signa la glande pin\u00e9ale comme le si\u00e8ge de notre \u00e2me.<\/p>\n

La m\u00e9latonine ne fut quant \u00e0 elle d\u00e9couverte qu\u2019en 1958 par le dermatologue Aaron Lerner pour faire ensuite l\u2019objet d\u2019\u00e9tudes intensives dans les ann\u00e9es 80. Lerner r\u00e9ussit \u00e0 isoler un composant dans une glande pin\u00e9ale bovine qui eut un effet blanchissant incroyable sur la peau des amphibiens, auquel il donna le nom de m\u00e9latonine. Ce fut \u00e9galement Lerner qui commen\u00e7a \u00e0 \u00e9tudier les effets de l\u2019hormone sur le sommeil. Apr\u00e8s une auto-exp\u00e9rimentation avec 100 mg de m\u00e9latonine, Lerner ne nota aucun effet secondaire autre que la somnolence. Dans les ann\u00e9es 60, on pensait que l\u2019alternance lumi\u00e8re\/obscurit\u00e9 \u00e9tait importante pour les mammif\u00e8res mais non pour les humains. Il faut attendre 1981 et la d\u00e9couverte d\u2019Alfred Lewy pour se rendre compte que la lumi\u00e8re forte pendant la nuit alt\u00e8re le niveau de m\u00e9latonine endog\u00e8ne chez les hommes. Cette d\u00e9couverte fut capitale pour la chronobiologie et la recherche sur la m\u00e9latonine. Au d\u00e9but des ann\u00e9es 90, une attention de plus en plus forte fut accord\u00e9e \u00e0 cette hormone avec un certain nombre d\u2019\u00e9tudes d\u00e9montrant les effets de la m\u00e9latonine sur diff\u00e9rents processus physiologiques comme la modulation immunitaire, la r\u00e9duction de la croissance des cellules tumorales, les radicaux libres et l\u2019influence sur les processus m\u00e9taboliques d\u00e9pendant du calcium. Il existe donc un certain nombre d\u2019autres recherches sur la m\u00e9latonine et ses multiples impacts sur la sant\u00e9 humaine.[\/vc_column_text][\/vc_column][vc_column width=\u00a0\u00bb1\/4″][vc_column_text]

\"MelatoninFACTS<\/a><\/p>\n<\/div>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row full_width=\u00a0\u00bbstretch_row\u00a0\u00bb el_class=\u00a0\u00bbbanner-top\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00a0\u00bb][vc_column][vc_custom_heading source=\u00a0\u00bbpost_title\u00a0\u00bb font_container=\u00a0\u00bbtag:h1|text_align:center\u00a0\u00bb use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00a0\u00bbmelatoninfacts2″][vc_column width=\u00a0\u00bb3\/4″][vc_column_text] Historie La m\u00e9latonine est une hormone secr\u00e9t\u00e9e par la glande pin\u00e9ale (glandula pinealis), un organe d\u00e9j\u00e0 mentionn\u00e9 par Galien de Pergame et autres \u00e9minences grecques au IIe si\u00e8cle. Au XVIe si\u00e8cle, le philosophe et scientifique fran\u00e7ais Descartes, d\u00e9signa la glande pin\u00e9ale comme le si\u00e8ge […]<\/p>\n","protected":false},"author":15,"featured_media":11663,"parent":18944,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"full-width-content","footnotes":""},"categories":[],"class_list":{"0":"post-18949","1":"page","2":"type-page","3":"status-publish","4":"has-post-thumbnail","6":"entry"},"acf":[],"yoast_head":"\nHistoire – Chronobiology.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dev.chronobiology.com\/fr\/melatonine-chronobiologie\/histoire\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Histoire\" \/>\n<meta property=\"og:description\" content=\"[vc_row full_width=\u00a0\u00bbstretch_row\u00a0\u00bb el_class=\u00a0\u00bbbanner-top\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00a0\u00bb][vc_column][vc_custom_heading source=\u00a0\u00bbpost_title\u00a0\u00bb font_container=\u00a0\u00bbtag:h1|text_align:center\u00a0\u00bb use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00a0\u00bbmelatoninfacts2″][vc_column width=\u00a0\u00bb3\/4″][vc_column_text] Historie La m\u00e9latonine est une hormone secr\u00e9t\u00e9e par la glande pin\u00e9ale (glandula pinealis), un organe d\u00e9j\u00e0 mentionn\u00e9 par Galien de Pergame et autres \u00e9minences grecques au IIe si\u00e8cle. 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