{"id":63802,"date":"2024-08-09T01:48:03","date_gmt":"2024-08-09T08:48:03","guid":{"rendered":"https:\/\/www.chronobiology.com\/deporte-o-tentempiecomo-decide-nuestro-cerebro\/"},"modified":"2024-08-29T07:10:03","modified_gmt":"2024-08-29T14:10:03","slug":"deporte-o-tentempiecomo-decide-nuestro-cerebro","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/deporte-o-tentempiecomo-decide-nuestro-cerebro\/","title":{"rendered":"\u00bfDeporte o tentempi\u00e9?C\u00f3mo decide nuestro cerebro"},"content":{"rendered":"

\u00bfDebo hacer deporte o prefiero ir a un caf\u00e9 y disfrutar de un delicioso batido de fresa?
\nLo que ocurre exactamente en nuestro cerebro cuando tomamos esta decisi\u00f3n ha sido un misterio para la ciencia hasta ahora, pero investigadores de la ETH de Z\u00farich han encontrado la soluci\u00f3n.
\nHan descifrado qu\u00e9 sustancia cerebral y qu\u00e9 c\u00e9lulas nerviosas median en esta decisi\u00f3n: el neurotransmisor orexina y las neuronas que lo producen.
\nEstos principios neurocient\u00edficos son relevantes porque muchas personas no hacen suficiente ejercicio.
\nProbablemente, la mayor\u00eda de nosotros hemos decidido en alg\u00fan momento saltarnos el ejercicio<\/a> en favor de una de las muchas tentaciones alternativas de la vida cotidiana.
\nSeg\u00fan la Organizaci\u00f3n Mundial de la Salud, el 80% de los adolescentes y el 27% de los adultos no hacen suficiente ejercicio.
\nY la obesidad est\u00e1 aumentando a un ritmo alarmante no s\u00f3lo entre los adultos, sino tambi\u00e9n entre los ni\u00f1os y adolescentes. <\/p>\n

La orexina desempe\u00f1a un papel clave a la hora de preferir la comida al ejercicio f\u00edsico<\/h2>\n

A pesar de estas estad\u00edsticas, muchas personas consiguen resistirse a las tentaciones siempre presentes y hacer suficiente ejercicio.
\nLos investigadores dirigidos por Denis Burdakov, catedr\u00e1tico de Neurociencia de la ETH de Z\u00farich, quer\u00edan saber qu\u00e9 hay en nuestro cerebro que nos ayuda a tomar estas decisiones.
\nEn sus experimentos con ratones, los investigadores pudieron demostrar que la orexina desempe\u00f1a un papel clave en este proceso.
\nEs uno de los m\u00e1s de cien neurotransmisores<\/a> activos en el cerebro.
\nOtros neurotransmisores, como la serotonina y la dopamina, se descubrieron hace mucho tiempo y su funci\u00f3n se ha descifrado en gran medida.
\nLa situaci\u00f3n es distinta con la orexina: los investigadores la descubrieron relativamente tarde, hace unos 25 a\u00f1os, y ahora est\u00e1n aclarando gradualmente sus funciones.
\nBurdakov es uno de los cient\u00edficos que ha investigado la orexina. \"Joven,Feliz,Hambrienta,Divertida,Alegre,Mujer,Vestida,Blanca,Ropa,Sujetando\"<\/a>Seg\u00fan los investigadores, la dopamina es una explicaci\u00f3n popular en neurociencia de por qu\u00e9 elegimos ciertas cosas y evitamos otras.
\nEsta sustancia mensajera del cerebro es crucial para nuestra motivaci\u00f3n general.
\nSin embargo, nuestros conocimientos actuales sobre la dopamina no explican f\u00e1cilmente por qu\u00e9 elegimos hacer ejercicio en vez de comer<\/a>.
\nNuestro cerebro libera dopamina tanto cuando comemos como cuando hacemos ejercicio, pero esto no explica por qu\u00e9 elegimos una cosa en vez de la otra.
\nPara averiguarlo<\/a>, los investigadores desarrollaron un ingenioso experimento conductual con ratones que pod\u00edan elegir libremente entre ocho opciones diferentes en pruebas de diez minutos.
\n\u00c9stas inclu\u00edan una rueda en la que pod\u00edan correr y una \u00abbarra de batidos\u00bb en la que pod\u00edan disfrutar de un batido normal con sabor a fresa.
\nEn su experimento, los cient\u00edficos compararon distintos grupos de ratones: un grupo con ratones normales y un grupo en el que el sistema de orexina de los ratones estaba bloqueado, bien con un f\u00e1rmaco o modificando gen\u00e9ticamente sus c\u00e9lulas.
\nLos ratones con un sistema de orexina intacto pasaron el doble de tiempo en la rueda de correr y la mitad en la barra de batidos que los ratones cuyo sistema de orexina estaba bloqueado.
\nCuriosamente, sin embargo, el comportamiento de los dos grupos no difer\u00eda en los experimentos en los que los cient\u00edficos s\u00f3lo ofrec\u00edan a los ratones la rueda corredora o el batido.
\nEsto significa que la funci\u00f3n principal del sistema de la orexina no es controlar cu\u00e1nto hacen ejercicio o cu\u00e1nto comen los ratones, sino que, seg\u00fan los investigadores, parece desempe\u00f1ar un papel central en la decisi\u00f3n entre una y otra cuando ambas opciones est\u00e1n disponibles.
\nSin orexina, la decisi\u00f3n era claramente a favor del batido, y los ratones renunciaban al ejercicio en favor de la comida<\/a>. <\/p>\n

Qu\u00e9 significa esto para los humanos<\/h2>\n

The ETH researchers assume that orexin could also be responsible for this decision in humans; the brain functions involved are known to be practically the same in both species.
\nAccording to Daria Peleg-Raibstein, group leader at ETH Zurich, who led the study together with Denis Burdakov, the next step will be to verify these results in humans.
\nThis could involve examining patients who have a restricted orexin system for genetic reasons – this is the case in around one in two thousand people.
\nThese people suffer from narcolepsy (a sleep disorder).<\/a> Another possibility would be to observe people who receive a drug that blocks orexin.
\nSuch drugs are approved for patients with insomnia.
\nBy understanding how the brain mediates between food intake and physical activity, the researchers say more effective strategies can be developed to combat the global obesity epidemic<\/a> and associated metabolic disorders.
\nIn particular, interventions could be developed to help overcome barriers to exercise in healthy people and those with limited physical activity.
\nHowever, Burdakov points out that these are important questions for scientists involved in human clinical research.
\nHe and his group are dedicated to basic neuroscience research.
\nNext, he wants to find out how the orexin neurons interact with the rest of the brain when making decisions like the one between exercise and snacking. <\/p>\n","protected":false},"excerpt":{"rendered":"

\u00bfDebo hacer deporte o prefiero ir a un caf\u00e9 y disfrutar de un delicioso batido de fresa? Lo que ocurre exactamente en nuestro cerebro cuando tomamos esta decisi\u00f3n ha sido un misterio para la ciencia hasta ahora, pero investigadores de la ETH de Z\u00farich han encontrado la soluci\u00f3n. Han descifrado qu\u00e9 sustancia cerebral y qu\u00e9 […]<\/p>\n","protected":false},"author":11,"featured_media":63431,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[212],"tags":[],"class_list":{"0":"post-63802","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-metabolismo-es","8":"entry"},"acf":[],"yoast_head":"\n\u00bfDeporte o tentempi\u00e9?C\u00f3mo decide nuestro cerebro – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"\u00bfDebo hacer deporte o prefiero ir a una cafeter\u00eda y disfrutar de un delicioso batido de fresa? 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