{"id":62005,"date":"2017-01-27T10:14:53","date_gmt":"2017-01-27T18:14:53","guid":{"rendered":"https:\/\/www.chronobiology.com\/insecticide-exposure-creating-higher-risk-diabetes-2\/"},"modified":"2024-07-21T22:14:47","modified_gmt":"2024-07-22T05:14:47","slug":"exposici-n-a-insecticidas-mayor-riesgo-de-diabetes-2","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/exposici-n-a-insecticidas-mayor-riesgo-de-diabetes-2\/","title":{"rendered":"Exposici\u00f3n a insecticidas: Mayor riesgo de diabetes"},"content":{"rendered":"

Hay muchas razones para limitar la exposici\u00f3n a los insecticidas. Seg\u00fan un nuevo estudio, entre ellas puede estar la interferencia con las v\u00edas de la melatonina y un mayor riesgo de diabetes.<\/p>\n

\u00bfCu\u00e1nto sabe sobre los ingredientes de sus insecticidas preferidos? El carbaril y el carbofurano son ingredientes comunes en muchos de ellos, y objeto de un estudio reciente. Estos insecticidas son qu\u00edmicamente similares a la melatonina, la hormona que regula el sue\u00f1o, el metabolismo y otros procesos biol\u00f3gicos importantes. De hecho, ambos son tan similares a la melatonina que pueden unirse a los receptores de melatonina<\/a> y provocar algunas de las mismas reacciones. Esta activaci\u00f3n de los receptores de melatonina puede provocar alteraciones del ritmo circadiano y s\u00edndrome metab\u00f3lico, entre otros efectos nocivos.<\/p>\n

Melatonina y radicales libres<\/h2>\n

La mayor\u00eda de la gente asocia la melatonina con el sue\u00f1o. Aunque esta hormona desempe\u00f1a un papel muy importante en la preparaci\u00f3n de nuestro cuerpo para el sue\u00f1o nocturno<\/a> y nos ayuda a obtener el descanso que necesitamos, tambi\u00e9n tiene otras funciones en la salud humana. La melatonina indica a nuestras c\u00e9lulas que ha llegado el momento de reparar el ADN, liberar las toxinas acumuladas durante el d\u00eda y recuperarse de forma que podamos despertarnos sinti\u00e9ndonos renovados. La melatonina tambi\u00e9n es muy importante en la regulaci\u00f3n de nuestras actividades metab\u00f3licas<\/a>. Esta es la raz\u00f3n por la que las personas que trabajan por turnos<\/a> o no duermen lo suficiente tienen un mayor riesgo de desarrollar diabetes y otras enfermedades metab\u00f3licas.<\/p>\n

Una de las funciones menos conocidas pero m\u00e1s importantes de la melatonina es la de eliminadora de radicales<\/a> libres o antioxidante. Nuestras c\u00e9lulas producen formas reactivas de ox\u00edgeno en las reacciones metab\u00f3licas diarias. Si no se eliminan, pueden da\u00f1ar las c\u00e9lulas de forma permanente. Peor a\u00fan, pueden da\u00f1ar el ADN y provocar c\u00e1ncer, as\u00ed como otras enfermedades graves. La melatonina nos protege de las toxinas que encontramos tanto en nuestro entorno como en nuestro propio cuerpo, adem\u00e1s de ayudarnos a descansar y regenerarnos. Dado que esta hormona desempe\u00f1a muchas funciones en la salud, la exposici\u00f3n a sustancias qu\u00edmicas que activan los receptores de melatonina puede ser destructiva para la salud.<\/p>\n

\u00bfC\u00f3mo pueden los insecticidas aumentar el riesgo de diabetes?<\/h2>\n

\"Insecticide<\/a>Si la melatonina es buena, \u00bfc\u00f3mo pueden ser malas las sustancias qu\u00edmicas que la imitan? Como en tantos otros \u00e1mbitos, el momento oportuno lo es todo. Tanto la cantidad de melatonina liberada como el momento en que se libera est\u00e1n estrechamente controlados en nuestro organismo, ya que son importantes para su funcionamiento. La melatonina se libera en cantidades muy espec\u00edficas y a horas muy concretas, en respuesta tanto a se\u00f1ales internas como a informaci\u00f3n de nuestro entorno. Cuando estos insecticidas se unen a los receptores de melatonina, inducen actividades en el momento y en las cantidades equivocadas. Adem\u00e1s, los circuitos de retroalimentaci\u00f3n negativa que rigen los niveles de melatonina pueden verse afectados, lo que conduce a una menor liberaci\u00f3n de melatonina cuando realmente se necesita.<\/p>\n

Seg\u00fan la autora principal del estudio, Margarita L. Dubocovitch PhD,<\/p>\n

\n

\u00abAl interactuar directamente con los receptores de melatonina en el cerebro y los tejidos perif\u00e9ricos, las sustancias qu\u00edmicas ambientales, como el carbaril, pueden alterar procesos fisiol\u00f3gicos clave que conducen a ritmos circadianos desajustados, patrones de sue\u00f1o y funciones metab\u00f3licas alteradas que aumentan el riesgo de enfermedades cr\u00f3nicas como la diabetes y los trastornos metab\u00f3licos\u00bb.<\/p>\n<\/blockquote>\n

Un nivel bajo de melatonina aumenta el riesgo de diabetes<\/a>, y la melatonina liberada a horas inadecuadas puede tener un efecto similar.<\/p>\n

\u00bfSon estos insecticidas los \u00fanicos productos qu\u00edmicos que tienen este efecto? Nuestro entorno est\u00e1 lleno de sustancias qu\u00edmicas que benefician nuestro modo de vida moderno. Sin embargo, estas sustancias qu\u00edmicas pueden interactuar con nuestro organismo de formas desconocidas o dif\u00edciles de comprender. Mientras tanto, limitar la exposici\u00f3n a estos dos insecticidas parece ser una forma importante de mantener un ritmo circadiano saludable y reducir el riesgo de diabetes y otras enfermedades metab\u00f3licas.<\/p>\n","protected":false},"excerpt":{"rendered":"

Hay muchas razones para limitar la exposici\u00f3n a los insecticidas. Seg\u00fan un nuevo estudio, entre ellas puede estar la interferencia con las v\u00edas de la melatonina y un mayor riesgo de diabetes. \u00bfCu\u00e1nto sabe sobre los ingredientes de sus insecticidas preferidos? El carbaril y el carbofurano son ingredientes comunes en muchos de ellos, y objeto […]<\/p>\n","protected":false},"author":15,"featured_media":25419,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[173,215,212,214,216],"tags":[],"class_list":{"0":"post-62005","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-el-ritmo-circadiano","8":"category-melatonina-es","9":"category-metabolismo-es","10":"category-sueno","11":"category-trabajo-por-turnos","12":"entry"},"acf":[],"yoast_head":"\nInsecticide Exposure: Creating Higher Risk for Diabetes<\/title>\n<meta name=\"description\" content=\"There are many reasons to limit your exposure to insecticides. 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