{"id":61486,"date":"2015-10-09T18:09:18","date_gmt":"2015-10-09T18:09:18","guid":{"rendered":"https:\/\/www.chronobiology.com\/chronopharmacology-hypertension-and-the-risk-of-diabetes\/"},"modified":"2024-07-19T12:54:30","modified_gmt":"2024-07-19T19:54:30","slug":"cronofarmacolog-a-hipertensi-n-y-riesgo-de-diabetes","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/cronofarmacolog-a-hipertensi-n-y-riesgo-de-diabetes\/","title":{"rendered":"Cronofarmacolog\u00eda, hipertensi\u00f3n y riesgo de diabetes"},"content":{"rendered":"
\n

Los estudios han demostrado repetidamente que la hipertensi\u00f3n, o tensi\u00f3n arterial alta, y la diabetes de tipo 2 est\u00e1n relacionadas. Aunque los cambios en el estilo de vida que tratan estas enfermedades son los mismos, como mejorar la dieta y aumentar el ejercicio, a\u00fan no se ha conseguido encontrar un f\u00e1rmaco que trate ambas enfermedades. Sin embargo, un nuevo estudio de cronofarmacolog\u00eda<\/a> sugiere que los medicamentos para la hipertensi\u00f3n administrados a determinadas horas del d\u00eda pueden ser eficaces para prevenir la diabetes de tipo 2.<\/p>\n

La relaci\u00f3n entre la hipertensi\u00f3n y la diabetes de tipo 2<\/h2>\n

\"Hypertension,<\/a>Las personas que padecen hipertensi\u00f3n tienen m\u00e1s probabilidades de desarrollar diabetes de tipo 2, y viceversa. Estas dos enfermedades forman parte de una dolencia que los profesionales sanitarios denominan s\u00edndrome metab\u00f3lico. Cuando las personas padecen estas dos enfermedades, corren un riesgo mucho mayor de desarrollar problemas cardiacos graves. La hipertensi\u00f3n puede causar problemas circulatorios, mientras que la diabetes aumenta el riesgo de aterosclerosis o endurecimiento de las arterias.<\/p>\n

Es importante abordar las distintas enfermedades que intervienen en el s\u00edndrome metab\u00f3lico como un conjunto, trabajando por la salud de todo el cuerpo. Dado que la diabetes y la hipertensi\u00f3n afectan a tantas personas y ambas est\u00e1n estrechamente relacionadas con el ritmo circ<\/a>adiano, se han convertido en un campo de estudio muy popular entre los investigadores de la biolog\u00eda circadiana.<\/p>\n

Tratamiento circadiano del s\u00edndrome metab\u00f3lico<\/h2>\n

Aunque la hipertensi\u00f3n y la diabetes de tipo 2 est\u00e1n claramente relacionadas, no se ha demostrado que el tratamiento de la hipertensi\u00f3n prevenga o trate la diabetes. Esto es lamentable porque el tratamiento de ambas enfermedades puede llevar mucho tiempo, ser agotador y requerir medicamentos diarios caros. Prevenir la diabetes es el mejor tratamiento, y por eso los investigadores de cronobiolog\u00eda<\/a> se alegraron de descubrir que tomar la medicaci\u00f3n para la tensi\u00f3n arterial a una hora determinada del d\u00eda reduce notablemente el riesgo de diabetes.<\/p>\n

Losinvestigadores de cronobiolog\u00eda estudiaron a m\u00e1s de 2.000 personas<\/a> con hipertensi\u00f3n que tomaban su medicaci\u00f3n a distintas horas del d\u00eda. Aunque la hora del d\u00eda no afectaba a la eficacia de la medicaci\u00f3n para reducir la tensi\u00f3n arterial, s\u00ed parec\u00eda afectar al riesgo de diabetes. Las personas que tomaban su medicaci\u00f3n antihipertensiva por la noche ten\u00edan muchas menos probabilidades de desarrollar diabetes de tipo 2.<\/p>\n

El momento de tomar la medicaci\u00f3n antihipertensiva<\/h2>\n

La mayor\u00eda de los m\u00e9dicos recomiendan que los pacientes tomen la medicaci\u00f3n para la tensi\u00f3n arterial por la ma\u00f1ana. Dado que las hormonas asociadas a la vigilia, como el cortisol, elevan la tensi\u00f3n arterial, la hipertensi\u00f3n tiende a ser m\u00e1s grave por la ma\u00f1ana. Sin embargo, las personas que tomaron su medicaci\u00f3n para la tensi\u00f3n arterial por la noche presentan en realidad una tensi\u00f3n arterial m\u00e1s baja a lo largo del d\u00eda y una menor fluctuaci\u00f3n de la tensi\u00f3n arterial. Adem\u00e1s, estas personas tienen un 65% menos de probabilidades de desarrollar diabetes de tipo 2, lo que conlleva una mayor salud y un menor riesgo de padecer una enfermedad cardiovascular grave.<\/p>\n

Bebedores y no bebedores<\/h2>\n

\"Chronopharmacology,<\/a>Adem\u00e1s de reducir el riesgo de diabetes y de futuras complicaciones cardiacas, tomar la medicaci\u00f3n para la tensi\u00f3n arterial por la noche puede ser especialmente \u00fatil para las personas conocidas como \u00ab<\/a>no hipertensas\u00bb. Los \u00abhipertensos no hipertensos\u00bb son personas con hipertensi\u00f3n que sufren un descenso de la tensi\u00f3n arterial por la noche, al igual que las personas con tensi\u00f3n arterial normal. Los \u00abno hipertensos\u00bb no sufren este descenso. Los no hipertensos no s\u00f3lo tienden a tener la tensi\u00f3n arterial m\u00e1s alta incluso con medicaci\u00f3n, sino que tienen m\u00e1s riesgo de padecer diabetes, cardiopat\u00edas y otras complicaciones asociadas a la hipertensi\u00f3n.<\/p>\n

\u00bfHay alg\u00fan inconveniente en tomar antihipertensivos por la noche? Los investigadores y los m\u00e9dicos a\u00fan no han encontrado ninguno. La medicaci\u00f3n no s\u00f3lo es m\u00e1s eficaz cuando se toma antes de acostarse, sino que tiene m\u00e1s probabilidades de ayudar a los no hipertensos, que son los m\u00e1s dif\u00edciles de tratar. Adem\u00e1s, reduce el riesgo de que los pacientes desarrollen diabetes de tipo 2, con todos los factores de riesgo que ello conlleva. Los pacientes que toman antihipertensivos pueden llevar ahora una vida m\u00e1s sana y larga gracias a este nuevo y apasionante estudio.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Los estudios han demostrado repetidamente que la hipertensi\u00f3n, o tensi\u00f3n arterial alta, y la diabetes de tipo 2 est\u00e1n relacionadas. Aunque los cambios en el estilo de vida que tratan estas enfermedades son los mismos, como mejorar la dieta y aumentar el ejercicio, a\u00fan no se ha conseguido encontrar un f\u00e1rmaco que trate ambas enfermedades. […]<\/p>\n","protected":false},"author":11,"featured_media":23887,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[208],"tags":[],"class_list":{"0":"post-61486","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-salud-del-corazon","8":"entry"},"acf":[],"yoast_head":"\nCronofarmacolog\u00eda, hipertensi\u00f3n y riesgo de diabetes – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"A new chronopharmacology study suggests that hypertensive medications given at certain times of day may be effective in preventing type 2 diabetes.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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