{"id":61426,"date":"2015-08-14T20:13:44","date_gmt":"2015-08-14T20:13:44","guid":{"rendered":"https:\/\/www.chronobiology.com\/wonder-hormone-improves-outcomes-in-cancer-patients\/"},"modified":"2024-07-19T12:53:38","modified_gmt":"2024-07-19T19:53:38","slug":"una-hormona-maravillosa-mejora-los-resultados-de-los-pacientes-con-c-ncer","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/una-hormona-maravillosa-mejora-los-resultados-de-los-pacientes-con-c-ncer\/","title":{"rendered":"Una hormona maravillosa mejora los resultados de los pacientes con c\u00e1ncer"},"content":{"rendered":"

La investigaci\u00f3n sobre el c\u00e1ncer ha dado lugar a muchos tratamientos nuevos e interesantes que mejoran los resultados al atacar los procesos bioqu\u00edmicos subyacentes a esta grave enfermedad. Aunque la melatonina <\/a>se utiliza desde hace d\u00e9cadas para tratar el insomnio y otros trastornos del sue\u00f1o, tambi\u00e9n puede ser un valioso tratamiento contra el c\u00e1ncer. Nuevos estudios sugieren que la melatonina inhibe el crecimiento tumoral al tiempo que disminuye los efectos secundarios de otros tratamientos contra el c\u00e1ncer.<\/p>\n

Melatonina: la multitarea definitiva<\/h2>\n

La melatonina es una de las hormonas m\u00e1s \u00abactivas\u00bb del cuerpo humano, ya que afecta a diversos procesos celulares vitales<\/a>. Ayuda a la reparaci\u00f3n celular, indica a las c\u00e9lulas que liberen diferentes hormonas seg\u00fan sea necesario y fomenta un ritmo circadiano<\/a> saludable, o reloj interno de 24 horas. Los niveles bajos de melatonina se han relacionado con enfermedades tan diversas como el c\u00e1ncer, las enfermedades neurodegenerativas e incluso los infartos de miocardio.<\/p>\n

A medida que el ser humano envejece, los niveles de melatonina disminuyen y aumenta la incidencia de muchas enfermedades. \u00bfEs una coincidencia? Nuevos estudios est\u00e1n demostrando que un nivel bajo de melatonina contribuye en realidad a muchas enfermedades asociadas con el envejecimiento, y que la administraci\u00f3n de suplementos de melatonina puede ser un tratamiento preventivo eficaz<\/a>.<\/p>\n

Melatonina y c\u00e1ncer<\/h2>\n

La edad no es la \u00fanica causa de los niveles bajos de melatonina. Cuando las personas sufren una privaci\u00f3n cr\u00f3nica del sue\u00f1o, como es habitual en la sociedad moderna, sus niveles de melatonina disminuyen y fluct\u00faan m\u00e1s. Las personas que no pueden dormir las horas nocturnas normales tienen un mayor riesgo de c\u00e1ncer<\/a>, raz\u00f3n por la cual la Organizaci\u00f3n Mundial de la Salud considera que el trabajo por turnos es cancer\u00edgeno.<\/p>\n

Aunque la relaci\u00f3n entre la alteraci\u00f3n del ritmo circadiano y el c\u00e1ncer est\u00e1 clara, hasta ahora se desconoc\u00eda el mecanismo de este mayor riesgo de c\u00e1ncer. Sin embargo, un nuevo metaan\u00e1lisis de estudios de cronobiolog\u00eda <\/a>sugiere que la melatonina ataca al c\u00e1ncer en sus cimientos, alterando los procesos bioqu\u00edmicos por los que crecen los tumores.<\/p>\n

\u00bfPodr\u00eda ser la melatonina el pr\u00f3ximo gran tratamiento contra el c\u00e1ncer?<\/h2>\n

\"Wonder<\/a>Un metaestudio sobre cronobiolog\u00eda<\/a> analiz\u00f3 investigaciones anteriores sobre la melatonina y recopil\u00f3 una larga lista de efectos anticancer\u00edgenos. La melatonina puede impedir la proliferaci\u00f3n de las c\u00e9lulas cancerosas desencadenando la apoptosis (o muerte celular programada) y cortando el suministro de sangre a los tumores. Adem\u00e1s, ya se sabe que la melatonina act\u00faa como antioxidante y mejora el sistema inmunitario, lo que impide el desarrollo del c\u00e1ncer. Por \u00faltimo, un nivel bajo de melatonina puede provocar niveles elevados de citoquinas, una mol\u00e9cula natural que se ha relacionado con el c\u00e1ncer.<\/p>\n

Cuando se administra melatonina a animales de laboratorio con tumores, el crecimiento de \u00e9stos se ralentiza considerablemente. Adem\u00e1s, los estudios est\u00e1n demostrando que los pacientes humanos con c\u00e1ncer toleran mejor otros tratamientos cuando toman un suplemento de melatonina. En un futuro pr\u00f3ximo, la melatonina podr\u00eda formar parte de un r\u00e9gimen est\u00e1ndar de tratamiento del c\u00e1ncer.<\/p>\n

Los investigadores en cronobiolog\u00eda y en diversos campos reconocen la promesa de la melatonina tanto para prevenir como para tratar el c\u00e1ncer. Sin embargo, sigue siendo dif\u00edcil conseguir financiaci\u00f3n para realizar estudios en este campo. En Estados Unidos, muchos estudios son realizados por intereses empresariales que quieren ganar dinero con los nuevos descubrimientos. Dado que la melatonina ya est\u00e1 ampliamente disponible y es asequible, no hay incentivos econ\u00f3micos para estudiarla. No obstante, cada vez se realizan m\u00e1s estudios sobre esta hormona multitarea, y casi todas las semanas se anuncian nuevos descubrimientos sobre la relaci\u00f3n entre el ritmo circadiano y la salud.<\/p>\n","protected":false},"excerpt":{"rendered":"

La investigaci\u00f3n sobre el c\u00e1ncer ha dado lugar a muchos tratamientos nuevos e interesantes que mejoran los resultados al atacar los procesos bioqu\u00edmicos subyacentes a esta grave enfermedad. Aunque la melatonina se utiliza desde hace d\u00e9cadas para tratar el insomnio y otros trastornos del sue\u00f1o, tambi\u00e9n puede ser un valioso tratamiento contra el c\u00e1ncer. Nuevos […]<\/p>\n","protected":false},"author":15,"featured_media":23723,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[200,215,201,214,216],"tags":[],"class_list":{"0":"post-61426","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-investigacion-sobre-el-cancer","8":"category-melatonina-es","9":"category-salud-celular","10":"category-sueno","11":"category-trabajo-por-turnos","12":"entry"},"acf":[],"yoast_head":"\nUna hormona maravillosa mejora los resultados de los pacientes con c\u00e1ncer – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"Cancer research has yielded many new and exciting treatments that improve outcomes by attacking the biochemical processes underlying this serious disease. 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