{"id":61340,"date":"2015-05-27T19:09:45","date_gmt":"2015-05-27T19:09:45","guid":{"rendered":"https:\/\/www.chronobiology.com\/digestive-disorders-and-your-internal-clock\/"},"modified":"2024-07-19T12:52:43","modified_gmt":"2024-07-19T19:52:43","slug":"los-trastornos-digestivos-y-su-reloj-interno","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/los-trastornos-digestivos-y-su-reloj-interno\/","title":{"rendered":"Los trastornos digestivos y su reloj interno"},"content":{"rendered":"

La cronobiolog\u00eda<\/a> es uno de los temas m\u00e1s estudiados de la medicina moderna. No es de extra\u00f1ar que la investigaci\u00f3n encuentre casi a diario nuevos v\u00ednculos entre el reloj interno del cuerpo y la salud. Sin embargo, incluso los cient\u00edficos m\u00e9dicos y los m\u00e9dicos pueden estar sorprendidos por los \u00faltimos hallazgos<\/a> que vinculan los ritmos circadianos y las enfermedades gastrointestinales comunes.<\/p>\n

Relojes internos y digesti\u00f3n<\/h2>\n

Los relojes internos existen principalmente para alinear los procesos biol\u00f3gicos con nuestro ciclo de sue\u00f1o-vigilia y para preparar nuestro cuerpo para los acontecimientos que probablemente se produzcan en determinados momentos del d\u00eda. Las retinas de nuestros ojos perciben la luz y transmiten una se\u00f1al al n\u00facleo supraquiasm\u00e1tico de nuestro cerebro, que a su vez dicta una serie de procesos hormonales y actividades fisiol\u00f3gicas. Ahora sabemos que alrededor del 10% de nuestros genes fluct\u00faan en actividad seg\u00fan la hora del d\u00eda, incluidos muchos implicados en la salud y la funci\u00f3n del tracto digestivo.<\/p>\n

La digesti\u00f3n es controlada y mantenida principalmente por los sistemas nerviosos parasimp\u00e1tico y simp\u00e1tico, que juntos se denominan sistema nervioso aut\u00f3nomo. Las investigaciones han descubierto que el sue\u00f1o no REM es cuando el sistema nervioso parasimp\u00e1tico, que estimula al cuerpo a digerir los alimentos, est\u00e1 m\u00e1s activo. El sistema nervioso simp\u00e1tico, que ralentiza la digesti\u00f3n, se alterna con el parasimp\u00e1tico durante el sue\u00f1o REM. Este equilibrio puede ser crucial para mantener una buena salud intestinal.<\/p>\n

La cronobiolog\u00eda de la alimentaci\u00f3n y la digesti\u00f3n<\/h2>\n

\"Digestive<\/a>Muchas de las hormonas asociadas al comportamiento alimentario y a la digesti\u00f3n, como la grelina, la insulina y la leptina, se liberan peri\u00f3dicamente a lo largo de un periodo de 24 horas. Sin embargo, en ausencia de luz, estos ciclos hormonales cesan. En lugar de liberarse hormonas cuando una persona est\u00e1 despierta y necesita comer, se liberan al azar. Dado que estas hormonas pueden ser destructivas sin alimentos en el est\u00f3mago, provocando as\u00ed la producci\u00f3n de \u00e1cido estomacal adicional, esto puede ser un factor subyacente en muchos tipos de enfermedades gastrointestinales y trastornos nutricionales.<\/p>\n

La falta de regulaci\u00f3n hormonal junto con la alternancia de ciclos de actividad auton\u00f3mica puede dar lugar a trastornos digestivos. Esto puede explicar en parte por qu\u00e9 los trabajadores por turnos y las personas con trastornos del sue\u00f1o circadiano tienen m\u00e1s probabilidades de sufrir alteraciones metab\u00f3licas como la diabetes de tipo 2 y tambi\u00e9n de ser obesos.<\/p>\n

Cuando el ritmo circadiano se tuerce<\/h2>\n

Estudios recientes sobre biolog\u00eda circadiana muestran una relaci\u00f3n entre los ciclos de sue\u00f1o alterados y trastornos intestinales comunes como el s\u00edndrome del intestino irritable. Hay varios factores que pueden explicarlo. En primer lugar, el \u00e1cido estomacal se libera en mayores cantidades cuando es estimulado por la actividad parasimp\u00e1tica. La interrupci\u00f3n de los ciclos<\/a> naturales de sue\u00f1o REM y no REM<\/a> puede impedir que el \u00e1cido estomacal se libere cuando es necesario para digerir los alimentos, lo que conduce a una menor absorci\u00f3n de nutrientes y a la desnutrici\u00f3n.<\/p>\n

\"DigestiveEn el otro extremo, las personas que tienen alterados estos ciclos del sue\u00f1o pueden, por el contrario, producir \u00e1cido en exceso y, por tanto, tener que convivir con reflujo gastrointestinal o \u00falceras del tracto digestivo superior. De hecho, en estudios recientes sobre biolog\u00eda circadiana se ha demostrado que las alteraciones de los ciclos de sue\u00f1o-vigilia provocan reflujo y el consiguiente da\u00f1o de la mucosa, as\u00ed como \u00falceras p\u00e9pticas.<\/p>\n

El s\u00edndrome del intestino irritable es otra enfermedad que ahora se sabe que est\u00e1 relacionada con la alteraci\u00f3n de los ritmos circadianos, o ciclos de aproximadamente 24 horas. Las personas que padecen un SII con diarrea predominante tienen una actividad auton\u00f3mica muy diferente de la fisiol\u00f3gica normal mientras duermen. Esta alteraci\u00f3n del ritmo puede tener efectos devastadores en la digesti\u00f3n.<\/p>\n

Un nuevo enfoque de los trastornos gastrointestinales<\/h2>\n

La esperanza que subyace a todos estos estudios de cronobiolog\u00eda es que el descubrimiento de las conexiones entre el ritmo circadiano<\/a> y la salud pueda conducir a un mejor diagn\u00f3stico y tratamiento. Por ejemplo, las personas que trabajan en turnos impares podr\u00edan ser sometidas a ex\u00e1menes m\u00e1s minuciosos para detectar el reflujo gastroesof\u00e1gico, con la esperanza de descubrir el trastorno porque da\u00f1a la mucosa. Adem\u00e1s, es posible que en el futuro a las personas con SII se les prescriba melatonina y fototerapia para corregir sus trastornos del sue\u00f1o, adem\u00e1s de los medicamentos disponibles actualmente.<\/p>\n

Todav\u00eda hay muchos estudios que analizan el v\u00ednculo biomolecular entre el ciclo sue\u00f1o-vigilia y los trastornos comunes del tubo digestivo. Sin embargo, la conexi\u00f3n entre ambos parece estar clara. Si no se duerme lo suficiente y con calidad, el riesgo de padecer un trastorno gastrointestinal es mayor.<\/p>\n","protected":false},"excerpt":{"rendered":"

La cronobiolog\u00eda es uno de los temas m\u00e1s estudiados de la medicina moderna. No es de extra\u00f1ar que la investigaci\u00f3n encuentre casi a diario nuevos v\u00ednculos entre el reloj interno del cuerpo y la salud. Sin embargo, incluso los cient\u00edficos m\u00e9dicos y los m\u00e9dicos pueden estar sorprendidos por los \u00faltimos hallazgos que vinculan los ritmos […]<\/p>\n","protected":false},"author":15,"featured_media":23459,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[209,212,214,216],"tags":[],"class_list":{"0":"post-61340","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-flora-intestinal-es","8":"category-metabolismo-es","9":"category-sueno","10":"category-trabajo-por-turnos","11":"entry"},"acf":[],"yoast_head":"\nLos trastornos digestivos y su reloj interno – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"Chronobiology is one of the most studied topics in modern medicine. 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