{"id":61318,"date":"2015-04-29T22:17:38","date_gmt":"2015-04-29T22:17:38","guid":{"rendered":"https:\/\/www.chronobiology.com\/research-shines-light-on-links-between-disrupted-circadian-rhythms-and-breast-cancer\/"},"modified":"2024-07-19T12:52:25","modified_gmt":"2024-07-19T19:52:25","slug":"una-investigaci-n-arroja-luz-sobre-la-relaci-n-entre-la-alteraci-n-del-ritmo-circadiano-y-el-c-ncer-de-mama","status":"publish","type":"post","link":"https:\/\/dev.chronobiology.com\/es\/una-investigaci-n-arroja-luz-sobre-la-relaci-n-entre-la-alteraci-n-del-ritmo-circadiano-y-el-c-ncer-de-mama\/","title":{"rendered":"Una investigaci\u00f3n arroja luz sobre la relaci\u00f3n entre la alteraci\u00f3n del ritmo circadiano y el c\u00e1ncer de mama"},"content":{"rendered":"

Aunque los investigadores siguen sin saber por qu\u00e9 los ritmos circadianos<\/a> desajustados pueden suponer una amenaza para el bienestar a largo plazo de las personas que sufren alteraciones prolongadas o recurrentes de los ciclos sue\u00f1o-vigilia, la ciencia demuestra continuamente que es un factor importante en una serie de enfermedades. En el caso de las mujeres, la alteraci\u00f3n del ritmo circadiano puede incluso aumentar el riesgo de c\u00e1ncer de mama<\/a>.<\/p>\n

Aunque los cient\u00edficos siguen trabajando para desentra\u00f1ar todos los interrogantes sobre c\u00f3mo afectan los ritmos circadianos a las c\u00e9lulas cancerosas, algunos estudios nuevos est\u00e1n arrojando luz sobre el tema como nunca antes.<\/p>\n

Luz artificial y melatonina<\/h2>\n

Uno de los principales culpables de todo este dilema es la luz artificial. Aunque los cient\u00edficos todav\u00eda no lo entienden todo sobre c\u00f3mo interact\u00faan la luz y la melatonina<\/a>, sus conocimientos van en aumento. Seg\u00fan el doctor Russell Foster<\/a>, del Imperial College School of Medicine de Londres:<\/p>\n

\n

\"Circadian<\/a>\u00abNo es la visi\u00f3n, sino alg\u00fan otro sistema de fototransducci\u00f3n en la retina el que provoca la supresi\u00f3n de la melatonina en respuesta a la luz\u00bb.<\/p>\n<\/blockquote>\n

Los cient\u00edficos han descubierto que la luz brillante regular por la noche<\/a> puede suprimir la producci\u00f3n de melatonina. La melatonina no s\u00f3lo inhibe el crecimiento del c\u00e1ncer, sino que los estudios sugieren que tambi\u00e9n aumenta la producci\u00f3n de estr\u00f3genos al tiempo que limita su receptividad. Su supresi\u00f3n puede desequilibrar hormonalmente el organismo.<\/p>\n

Los m\u00e9dicos saben que un desequilibrio hormonal puede inclinar f\u00e1cilmente la balanza hacia el c\u00e1ncer de mama. Comprender los mecanismos por los que esas hormonas se desequilibran es imprescindible para cualquier programa de prevenci\u00f3n, y esta nueva informaci\u00f3n puede proporcionar a las mujeres consejos pr\u00e1cticos. Si las mujeres se ci\u00f1en a los horarios normales de luz diurna y evitan las profesiones que requieren pasar largas horas bajo luces artificiales mientras el cuerpo pide a gritos dormir, pueden tener muchas m\u00e1s posibilidades de evitar el c\u00e1ncer de mama.<\/p>\n

C\u00f3mo sabemos que la luz artificial es la culpable<\/h2>\n

Una prueba de que la luz artificial es culpable de introducir el desequilibrio circadiano es que las mujeres ciegas tienen una marcada ventaja<\/a> a la hora de evitar el c\u00e1ncer de mama. Seg\u00fan el doctor Richard Stevens, presidente de la conferencia de los NIH y epidemi\u00f3logo del c\u00e1ncer:<\/p>\n

\n

\u00abInicialmente se pens\u00f3 que las mujeres ciegas podr\u00edan tener un mayor riesgo de desarrollar c\u00e1ncer de mama, porque algunos estudios han informado de que tienen una menarquia m\u00e1s temprana y un retraso en la edad f\u00e9rtil, ambos factores que se ha visto que aumentan el riesgo de c\u00e1ncer de mama en las mujeres, sin embargo, se ha encontrado que estas mujeres tienen un menor riesgo de desarrollar la enfermedad.\u00bb<\/p>\n<\/blockquote>\n

\"Circadian<\/a>Stevens y sus colegas han anunciado recientemente sus hallazgos, que demuestran que cuanto m\u00e1s discapacitada visual es una mujer, menos probabilidades tiene de que le diagnostiquen un c\u00e1ncer. Esta investigaci\u00f3n, unida al descubrimiento de que las mujeres que suelen trabajar en el turno de noche tienen una incidencia considerablemente mayor de c\u00e1ncer de mama, sugiere a los cient\u00edficos que la supresi\u00f3n de melatonina es consecuencia de la exposici\u00f3n a la luz artificial en mitad de la noche.<\/p>\n

Mientras que las mujeres que ejercen profesiones como la de azafata de vuelo suelen tener una mayor incidencia de c\u00e1ncer de mama que otras trabajadoras del primer turno, las personas ciegas o con discapacidad visual disfrutan de una disminuci\u00f3n del 15 por ciento en la incidencia de c\u00e1ncer. Aunque las razones de esto no se entienden del todo, un ritmo circadiano desajustado causado por la incidencia de la luz en los momentos equivocados tiene un impacto, y los cient\u00edficos est\u00e1n trabajando duro para entender los v\u00ednculos m\u00e1s plenamente.<\/p>\n

Para las mujeres interesadas en prevenir el c\u00e1ncer de mama, la opci\u00f3n obvia deber\u00eda ser ce\u00f1irse a las horas de luz diurna y evitar las luces brillantes en mitad de la noche. Aunque muchas mujeres podr\u00edan pensar que est\u00e1n fuera de peligro porque no trabajan en el turno de noche, tambi\u00e9n deber\u00edan tener cuidado y evitar quedarse despiertas hasta tarde mirando el m\u00f3vil o la televisi\u00f3n, ya que la luz artificial de muchos tipos puede suprimir la melatonina que protege el cuerpo y mantiene estables los niveles hormonales.<\/p>\n

A medida que se pone m\u00e1s \u00e9nfasis en comprender la cronobiolog\u00eda<\/a> y c\u00f3mo el cuerpo humano se ve afectado por los ritmos circadianos, es probable que muchos otros problemas de salud que han preocupado a las personas durante d\u00e9cadas demuestren tener un v\u00ednculo con la biolog\u00eda circadiana. Esto demuestra que los antiguos ten\u00edan raz\u00f3n cuando dec\u00edan: \u00abPara todo hay una estaci\u00f3n, y un tiempo para cada prop\u00f3sito bajo el cielo\u00bb.<\/p>\n

Incluso hay un tiempo para despertarse y otro para dormir.<\/p>\n","protected":false},"excerpt":{"rendered":"

Aunque los investigadores siguen sin saber por qu\u00e9 los ritmos circadianos desajustados pueden suponer una amenaza para el bienestar a largo plazo de las personas que sufren alteraciones prolongadas o recurrentes de los ciclos sue\u00f1o-vigilia, la ciencia demuestra continuamente que es un factor importante en una serie de enfermedades. En el caso de las mujeres, […]<\/p>\n","protected":false},"author":15,"featured_media":23359,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[200,215,217,214,216],"tags":[],"class_list":{"0":"post-61318","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-investigacion-sobre-el-cancer","8":"category-melatonina-es","9":"category-salud-de-la-mujer","10":"category-sueno","11":"category-trabajo-por-turnos","12":"entry"},"acf":[],"yoast_head":"\nUna investigaci\u00f3n arroja luz sobre la relaci\u00f3n entre la alteraci\u00f3n del ritmo circadiano y el c\u00e1ncer de mama – Chronobiology.com<\/title>\n<meta name=\"description\" content=\"Although researchers are still in the dark about why misaligned circadian rhythms can pose such a threat to the long term well-being of individuals who experience prolonged or recurring disrupted sleep\/wake cycles, science is continually showing that it is an important factor in a number of maladies. 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