{"id":18679,"date":"2017-01-22T22:01:23","date_gmt":"2017-01-23T06:01:23","guid":{"rendered":"https:\/\/www.chronobiology.com\/historia\/"},"modified":"2020-06-18T07:46:20","modified_gmt":"2020-06-18T14:46:20","slug":"historia","status":"publish","type":"page","link":"https:\/\/dev.chronobiology.com\/es\/melatonina-y-cronobiologia\/historia\/","title":{"rendered":"Historia"},"content":{"rendered":"

[vc_row full_width=\u00bbstretch_row\u00bb el_class=\u00bbbanner-top\u00bb css=\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00bb][vc_column][vc_custom_heading source=\u00bbpost_title\u00bb font_container=\u00bbtag:h1|text_align:center\u00bb use_theme_fonts=\u00bbyes\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00bbmelatoninfacts2″][vc_column width=\u00bb3\/4″][vc_column_text]<\/p>\n

Historia<\/h2>\n

La melatonina es una sustancia producida por la gl\u00e1ndula pineal (ep\u00edfisis). Este \u00f3rgano fue mencionado por primera vez por Galeno de P\u00e9rgamo y por otros griegos del siglo II despu\u00e9s de Cristo. En el siglo XVI, el fil\u00f3sofo y cient\u00edfico franc\u00e9s Descartes describi\u00f3 la gl\u00e1ndula pineal como la \u00absede del alma\u00bb.<\/p>\n

La melatonina en s\u00ed fue descubierta por primera vez en 1958 por un dermat\u00f3logo llamado Aaron Lerner y se ha estudiado ampliamente a partir de principios de los a\u00f1os 80. Lerner logr\u00f3 extraer de una gl\u00e1ndula pineal bovina una sustancia que ten\u00eda un fuerte efecto blanqueador en la piel de los anfibios, y llam\u00f3 esta sustancia \u00abmelatonina\u00bb. Fue otra vez Lerner quien empez\u00f3 a estudiar los efectos que esta hormona puede tener en el sue\u00f1o. La prob\u00f3 sobre s\u00ed mismo, tomando 100 mg y no detect\u00f3 ning\u00fan efecto secundario a excepci\u00f3n de un estado de somnolencia. En los a\u00f1os 60, todav\u00eda se supon\u00eda que el ritmo luz-oscuridad era importante para todos los mam\u00edferos, excepto el hombre. S\u00f3lo en 1981, Alfred Lewy descubri\u00f3 que la exposici\u00f3n a una luz intensa durante la noche inhibe la producci\u00f3n end\u00f3gena de melatonina en los seres humanos. Este descubrimiento fue un punto de inflexi\u00f3n fundamental para la cronobiolog\u00eda y para la investigaci\u00f3n sobre la melatonina. A principios de los a\u00f1os 90, la melatonina recibi\u00f3 una atenci\u00f3n creciente a medida que los estudios mostraban sus efectos sobre los diferentes procesos del organismo, como la inmunomodulaci\u00f3n, la inhibici\u00f3n del crecimiento tumoral, el bloqueo de los radicales libres y la influencia sobre los procesos metab\u00f3licos del calcio. Sucesivamente se llevaron a cabo otros estudios sobre la melatonina y sus m\u00faltiples efectos en la salud humana.[\/vc_column_text][\/vc_column][vc_column width=\u00bb1\/4″][vc_column_text]

\"MelatoninFACTS<\/a><\/p>\n<\/div>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row full_width=\u00bbstretch_row\u00bb el_class=\u00bbbanner-top\u00bb css=\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00bb][vc_column][vc_custom_heading source=\u00bbpost_title\u00bb font_container=\u00bbtag:h1|text_align:center\u00bb use_theme_fonts=\u00bbyes\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00bbmelatoninfacts2″][vc_column width=\u00bb3\/4″][vc_column_text] Historia La melatonina es una sustancia producida por la gl\u00e1ndula pineal (ep\u00edfisis). Este \u00f3rgano fue mencionado por primera vez por Galeno de P\u00e9rgamo y por otros griegos del siglo II despu\u00e9s de Cristo. En el siglo XVI, el fil\u00f3sofo y cient\u00edfico franc\u00e9s Descartes describi\u00f3 […]<\/p>\n","protected":false},"author":15,"featured_media":25015,"parent":18674,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"full-width-content","footnotes":""},"categories":[],"class_list":{"0":"post-18679","1":"page","2":"type-page","3":"status-publish","4":"has-post-thumbnail","6":"entry"},"acf":[],"yoast_head":"\nHistoria – Chronobiology.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dev.chronobiology.com\/es\/melatonina-y-cronobiologia\/historia\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Historia\" \/>\n<meta property=\"og:description\" content=\"[vc_row full_width=\u00bbstretch_row\u00bb el_class=\u00bbbanner-top\u00bb css=\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00bb][vc_column][vc_custom_heading source=\u00bbpost_title\u00bb font_container=\u00bbtag:h1|text_align:center\u00bb use_theme_fonts=\u00bbyes\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00bbmelatoninfacts2″][vc_column width=\u00bb3\/4″][vc_column_text] Historia La melatonina es una sustancia producida por la gl\u00e1ndula pineal (ep\u00edfisis). Este \u00f3rgano fue mencionado por primera vez por Galeno de P\u00e9rgamo y por otros griegos del siglo II despu\u00e9s de Cristo. 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\/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Historia – Chronobiology.com","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/dev.chronobiology.com\/es\/melatonina-y-cronobiologia\/historia\/","og_locale":"es_ES","og_type":"article","og_title":"Historia","og_description":"[vc_row full_width=\u00bbstretch_row\u00bb el_class=\u00bbbanner-top\u00bb css=\u00bb.vc_custom_1479388656340{background-image: url(https:\/\/www.chronobiology.com\/wp-content\/uploads\/2016\/11\/melatonin-banner.jpg?id=11663) !important;}\u00bb][vc_column][vc_custom_heading source=\u00bbpost_title\u00bb font_container=\u00bbtag:h1|text_align:center\u00bb use_theme_fonts=\u00bbyes\u00bb][\/vc_column][\/vc_row][vc_row el_class=\u00bbmelatoninfacts2″][vc_column width=\u00bb3\/4″][vc_column_text] Historia La melatonina es una sustancia producida por la gl\u00e1ndula 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